July 2023 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Spondylolisthesis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Spondylolisthesis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Spondylolisthesis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Spondylolisthesis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:Modified unilateral iliac screw fixation with partial reduction in the treatment of high-grade spondylolisthesis at L5/S1 in adult patients: introduction of key technique, report of clinical outcomes and analysis of spinopelvic parameters.
Authors:Zhang Y, Song J, Lu Y, Yi M, Lin W, Yao M, Luo Z, Zhang G, Ding L
Institution:Department of Spinal Surgery, Beijing Shijitan Hospital, Capital Medical University, No.10, Tieyi Road, Yangfangdian, Haidian District, Beijing, 10038, People's Republic of China. dinglx@bjsjth.cn.
Journal:BMC Musculoskelet Disord. 2023 Jun 2;24(1):451. doi: 10.1186/s12891-023-06552-1.

2:Spondylolysis among Patients Without Low Back Pain in a Diagnostic Centre: A Descriptive Cross-sectional Study.
Authors:Sharma B, Panta OB, Thapa BR, Thapa S
Institution:Department of Radiology and Imaging, Bheri Hospital, Banke, Nepalgunj, Nepal.; Department of Radiology, Lumbini Province Hospital, Butwal, Rupandehi, Nepal.
Journal:JNMA J Nepal Med Assoc. 2023 Feb 1;61(258):123-126. doi: 10.31729/jnma.8022.

3:Safety and Efficacy of Cortical Bone Trajectory Screw Fixation Combined with Facet Fusion for the Treatment of Lumbar Degenerative Disease.
Authors:Kong X, Li B, Xu L, Li J, Gao C, Wu D, Ma S, Song Y, Zhao J, Wang X
Institution:Health Management Center, The Second Hospital of Shandong University, Shandong, People's Republic of China.; Nursing Department, The Second Hospital of Shandong University, Shandong, People's Republic of China.
Journal:Orthop Surg. 2023 Jun;15(6):1617-1626. doi: 10.1111/os.13752. Epub 2023 May 18.

4:Clinical and Radiographic Comparison of Oblique Lateral Lumbar Interbody Fusion and Minimally Invasive Transforaminal Lumbar Interbody Fusion in Patients with L4/5 grade-1 Degenerative Spondylolisthesis.
Authors:He D, He W, Tian W, Liu B, Liu Y, Sun Y, Xing Y, Lang Z, Wang Y, Ma T, Liu M
Institution:Department of Spine Surgery, Beijing Jishuitan Hospital, Beijing, China.
Journal:Orthop Surg. 2023 Jun;15(6):1477-1487. doi: 10.1111/os.13360. Epub 2023 May 8.

5:Response to Preoperative Steroid Injections Predicts Surgical Outcomes in Patients Undergoing Fusion for Isthmic Spondylolisthesis.
Authors:Turtle J, Randell Z, Karamian B, Spiker WR, Lawrence B, Brodke D, Spina N
Institution:Department of Orthopaedics, University of Utah, Salt Lake City, UT.
Journal:Spine (Phila Pa 1976). 2023 Jul 1;48(13):914-919. doi: 10.1097/BRS.0000000000004687. Epub 2023 Apr 17.

6:A systematic review of anterior lumbar interbody fusion (ALIF) versus posterior lumbar interbody fusion (PLIF), transforaminal lumbar interbody fusion (TLIF), posterolateral lumbar fusion (PLF).
Authors:Rathbone J, Rackham M, Nielsen D, Lee SM, Hing W, Riar S, Scott-Young M
Institution:Faculty of Health Science & Medicine, Bond University, Gold Coast, Australia. swalter@goldcoastspine.com.au.
Journal:Eur Spine J. 2023 Jun;32(6):1911-1926. doi: 10.1007/s00586-023-07567-x. Epub 2023 Apr 18.

7:Laminectomy With Fusion is Associated With Greater Functional Improvement Compared With Laminectomy Alone for the Treatment of Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-Analysis.
Authors:Shukla GG, Chilakapati SS, Matur AV, Palmisciano P, Conteh F, Onyewadume L, Duah H, Griffith A, Tao X, Vorster P, Gupta S, Cheng J, Motley B, Adogwa O
Institution:Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH.
Journal:Spine (Phila Pa 1976). 2023 Jun 15;48(12):874-884. doi: 10.1097/BRS.0000000000004673. Epub 2023 Apr 6.

8:Reduction of spondylolisthesis and restoration of lumbar lordosis after anterior lumbar interbody fusion (ALIF).
Authors:Aspalter S, Stefanits H, Maier CJ, Radl C, Wagner H, Hermann P, Aichholzer M, Stroh N, Gruber A, Senker W
Institution:Department of Neurosurgery, Kepler University Hospital Linz, Johannes Kepler University, Linz, Austria.
Journal:BMC Surg. 2023 Mar 27;23(1):66. doi: 10.1186/s12893-023-01966-z.

9:Factors influencing the long-term outcomes of instrumentation surgery for degenerative lumbar spondylolisthesis: a post-hoc analysis of a prospective randomized study.
Authors:Inose H, Kato T, Matsukura Y, Hirai T, Yoshii T, Kawabata S, Takahashi K, Okawa A
Institution:Department of Orthopedic and Trauma Research, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. Electronic address: inose.orth@tmd.ac.jp.; Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
Journal:Spine J. 2023 Jun;23(6):799-804. doi: 10.1016/j.spinee.2023.02.002. Epub 2023 Feb 11.

10:Patient's expectations of surgery for lumbar degenerative spondylolisthesis: analysis by type of surgery and patient factors from the Canadian Spine Outcomes and Research Network (CSORN).
Authors:Dandurand C, Urquhart J, Bailey CS, Ailon T, Charest-Morin R, Dea N, Dvorak M, Glennie A, Kwon BK, Paquette S, Rampersaud YR, Street JT, Hounjet C, Mashayekhi MS, Fisher CG
Institution:Department of Orthopedics Surgery, Combined Neurosurgical and Orthopedic Spine Program, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: Charlotte.dandurand@vch.ca.
Journal:Spine J. 2023 Jun;23(6):805-815. doi: 10.1016/j.spinee.2023.01.018. Epub 2023 Feb 9.

11:Clinical outcome in decompression alone versus decompression and instrumented fusion in patients with isthmic spondylolisthesis: a prospective cohort study.
Authors:Azizpour K, Schutte PJ, Arts MP, Pondaag W, Bouma GJ, Coppes M, Steyerberg EW, Peul WC, Vleggeert-Lankamp CLA
Institution:1Department of Neurosurgery, Leiden University Medical Center, Leiden, Zuid-Holland.
Journal:J Neurosurg Spine. 2023 Feb 3;38(5):573-584. doi: 10.3171/2022.12.SPINE22808. Print 2023 May 1.

12:Foraminoplasty with Partial Pediculectomy in Degenerative Spondylolisthesis Cases with Nerve Compression.
Authors:Akgun MY, Toklu S, Gunerbuyuk C, Ates O, Aydin AL, Baran O, Oktenoglu T, Sasani M, Ozer AF
Institution:Department of Neurosurgery, Koc University Hospital, Istanbul, Turkey; Spine Center, Koc University Hospital, Istanbul, Turkey. Electronic address: myigitakgun@gmail.com.
Journal:World Neurosurg. 2023 Apr;172:e532-e539. doi: 10.1016/j.wneu.2023.01.073. Epub 2023 Jan 23.

13:High preoperative expectations and postoperative fulfillment of expectations two years after decompression alone and decompression plus fusion for lumbar degenerative spondylolisthesis.
Authors:Duculan R, Fong AM, Cammisa FP, Sama AA, Hughes AP, Lebl DR, Mancuso CA, Girardi FP
Institution:Hospital for Special Surgery, Department of Orthopedic Surgery, 535 East 70th Street, New York, NY.
Journal:Spine J. 2023 May;23(5):665-674. doi: 10.1016/j.spinee.2023.01.006. Epub 2023 Jan 13.

14:Decompression alone versus decompression with fusion in patients with lumbar spinal stenosis with degenerative spondylolisthesis: a systematic review and meta-analysis.
Authors:Gadjradj PS, Basilious M, Goldberg JL, Sommer F, Navarro-Ramirez R, Mykolajtchuk C, Ng AZ, Medary B, Hussain I, Härtl R
Institution:Department of Neurological Surgery, Brain and Spine Center, Weill Cornell, New York, NY, USA. p.gadjradj@erasmusmc.nl.
Journal:Eur Spine J. 2023 Mar;32(3):1054-1067. doi: 10.1007/s00586-022-07507-1. Epub 2023 Jan 6.

15:Minimally invasive versus open transforaminal lumbar interbody fusion for grade I lumbar spondylolisthesis: 5-year follow-up from the prospective multicenter Quality Outcomes Database registry.
Authors:Chan AK, Bydon M, Bisson EF, Glassman SD, Foley KT, Shaffrey CI, Potts EA, Shaffrey ME, Coric D, Knightly JJ, Park P, Wang MY, Fu KM, Slotkin JR, Asher AL, Virk MS, Michalopoulos GD, Guan J, Haid RW, Agarwal N, Park C, Chou D, Mummaneni PV
Institution:1Department of Neurological Surgery, Columbia University, The Och Spine Hospital at NewYork-Presbyterian, New York, New York.; 15Department of Neurological Surgery, University of California, San Francisco, California; and.
Journal:Neurosurg Focus. 2023 Jan;54(1):E2. doi: 10.3171/2022.10.FOCUS22602.

16:A Review of the Main Classifications of Lumbar Spondylolisthesis.
Authors:Lan Z, Yan J, Yang Y, Xu Q, Jin Q
Institution:Ningxia Medical University, The General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China; Orthopedics Ward 3, The General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China. Electronic address: lzb360999@163.com.
Journal:World Neurosurg. 2023 Mar;171:94-102. doi: 10.1016/j.wneu.2022.12.104. Epub 2022 Dec 28.

17:Fusion and clinical outcomes of lumbar interbody fusion for low-grade isthmic spondylolisthesis.
Authors:Ould-Slimane M, Prost S, d'Astorg H, Lalevée M, Blondel B, Szadkowski M, Fuentes S, Collinet A, Parent HF, Litrico S, Grelat M, Zairi F, Charles YP, Giorgi H
Institution:Department of Orthopedic Surgery, Spine Unit, Rouen University Hospital, Rouen, France. Electronic address: mourad.ould-slimane@chu-rouen.fr.; Institut Mediterraneen du Dos, Marseille, France.
Journal:Orthop Traumatol Surg Res. 2023 Apr;109(2):103508. doi: 10.1016/j.otsr.2022.103508. Epub 2022 Dec 7.

18:Long-Term Clinical and Imaging Results of Oblique Lateral Interbody Fusion for Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-Analysis.
Authors:Ma H, Zhang F, Ying Q, Pan B, Li Y, Ge H, Cao Y, Jiang T, Dai M, Ji C
Institution:School of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Journal:Orthop Surg. 2023 Feb;15(2):400-412. doi: 10.1111/os.13588. Epub 2022 Dec 7.

19:Surgical management of high-grade paediatric spondylolisthesis: meta-analysis and systematic review.
Authors:Koucheki R, Rocos B, Gandhi R, Lewis SJ, Lebel DE
Institution:Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. david.lebel@sickkids.ca.
Journal:Eur Spine J. 2023 Feb;32(2):436-446. doi: 10.1007/s00586-022-07408-3. Epub 2022 Oct 5.

20:A Prospective Study of Lumbar Facet Arthroplasty in the Treatment of Degenerative Spondylolisthesis and Stenosis: Results from the Total Posterior Spine System (TOPS) IDE Study.
Authors:Pinter ZW, Freedman BA, Nassr A, Sebastian AS, Coric D, Welch WC, Steinmetz MP, Robbins SE, Ament J, Anand N, Arnold P, Baron E, Huang J, Whitmore R, Whiting D, Tahernia D, Sandhu F, Chahlavi A, Cheng J, Chi J, Pirris S, Groff M, Fabi A, Meyer S, Kushwaha V, Kent R, DeLuca S, Smorgick Y, Anekstein Y
Institution:Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.; Shamir Medical Center, Zerifin, Israel, affiliated with the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv Israel.
Journal:Clin Spine Surg. 2023 Mar 1;36(2):E59-E69. doi: 10.1097/BSD.0000000000001365. Epub 2022 Aug 3.

21:Prospective, randomized controlled multicenter study of posterior lumbar facet arthroplasty for the treatment of spondylolisthesis.
Authors:Coric D, Nassr A, Kim PK, Welch WC, Robbins S, DeLuca S, Whiting D, Chahlavi A, Pirris SM, Groff MW, Chi JH, Huang JH, Kent R, Whitmore RG, Meyer SA, Arnold PM, Patel AI, Orr RD, Krishnaney A, Boltes P, Anekstein Y, Steinmetz MP
Institution:1Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina.; 16Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio; and.
Journal:J Neurosurg Spine. 2022 Sep 23;38(1):115-125. doi: 10.3171/2022.7.SPINE22536. Print 2023 Jan 1.

22:Comparison of robot-assisted versus fluoroscopy-assisted minimally invasive transforaminal lumbar interbody fusion for degenerative lumbar spinal diseases: 2-year follow-up.
Authors:Wang L, Li C, Wang Z, Li D, Tian Y, Yuan S, Liu X
Institution:Department of Orthopedics, Qilu Hospital of Shandong University, Wenhua West Road 107#, Jinan, 250012, Shandong, People's Republic of China. newyuliu@163.com.
Journal:J Robot Surg. 2023 Apr;17(2):473-485. doi: 10.1007/s11701-022-01442-5. Epub 2022 Jul 5.

23:Comparison of spinous process-splitting laminectomy versus posterolateral fusion for lumbar degenerative spondylolisthesis.
Authors:Kurogochi D, Uehara M, Yui M, Ikegami S, Oba H, Mimura T, Takizawa T, Fukuzawa T, Hayashi K, Kosaku H, Hatakenaka T, Kamanaka T, Miyaoka Y, Misawa H, Takahashi J
Institution:Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.
Journal:Eur Spine J. 2023 Feb;32(2):447-454. doi: 10.1007/s00586-022-07298-5. Epub 2022 Jul 5.

24:To fuse or not to fuse: The elderly patient with lumbar stenosis and low-grade spondylolisthesis. Systematic review and meta-analysis of randomised controlled trials.
Authors:Abdel-Fattah AR, Bell F, Boden L, Ferry J, McCormick C, Ross M, Cameron I, Smith T, Baliga S, Myint PK
Institution:Ageing Clinical and Experimental Research (ACER) Team, Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK; School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK.; Ageing Clinical and Experimental Research (ACER) Team, Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK. Electronic address: phyo.myint@abdn.ac.uk.
Journal:Surgeon. 2023 Feb;21(1):e23-e31. doi: 10.1016/j.surge.2022.02.008. Epub 2022 Mar 16.

25:Spondylolisthesis in young patients: postoperative functional outcomes at 22-year mean follow-up.
Authors:Barone G, Scaramuzzo L, Giudici F, Manzini F, Minoia L, Archetti M, Zagra A
Institution:Spine Surgery Division 1, IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 6, 20161, Milan, Italy. giuseppebarone.gale@gmail.com.
Journal:Arch Orthop Trauma Surg. 2023 Jan;143(1):97-106. doi: 10.1007/s00402-021-04006-8. Epub 2021 Jun 22.

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