Chronic Pancreatitis
July 2023 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Painless form of chronic pancreatitis - multicentre study.
Authors:Dite P, Precechtelova M, Bojkova M, Lovecek M, Ambroz R, Martinek A, Dolina J
Institution:Department of Gastroenterology and Internal Medicine, University Hospital Brno, Czech Republic.
Journal:Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2023 Jun;167(2):157-161. doi: 10.5507/bp.2023.019. Epub 2023 May 22.

2:Clinical and paraclinical characteristics in pediatric patients with acute recurrent and chronic pancreatitis: a cohort in Mexico.
Authors:Argüello-López JA, García-Cárdenas ES, Miranda-Lora AL, Blanco-Rodríguez G
Institution:Departamento de Gastroenterologia y Nutricion.; Departamento de Cirugia de Torax y Endoscopia, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico.
Journal:Bol Med Hosp Infant Mex. 2023;80(2):122-128. doi: 10.24875/BMHIM.22000144.

3:Changing trends in the minimally invasive surgery for chronic pancreatitis.
Authors:Kalayarasan R, Shukla A
Institution:Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry 605006, India. kalayarasanraja@yahoo.com.
Journal:World J Gastroenterol. 2023 Apr 14;29(14):2101-2113. doi: 10.3748/wjg.v29.i14.2101.

4:Chronic pancreatitis and nutritional support.
Authors:Campagnola P, de Pretis N, Zorzi A, Caldart F, Frulloni L
Institution:Department of Medicine, University of Verona, Verona, Italy. Electronic address: pietro.campagnola@aovr.veneto.it.
Journal:Best Pract Res Clin Gastroenterol. 2023 Feb-Mar;62-63:101823. doi: 10.1016/j.bpg.2023.101823. Epub 2023 Feb 3.

5:Osteoporosis and sarcopenia are common and insufficiently diagnosed among chronic pancreatitis patients.
Authors:Parhiala M, Ukkonen M, Sand J, Laukkarinen J
Institution:Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. mikael.parhiala@tuni.fi.
Journal:BMC Gastroenterol. 2023 Apr 13;23(1):124. doi: 10.1186/s12876-023-02756-w.

6:Pancreatic exocrine insufficiency is a risk factor for kidney stones in patients with chronic pancreatitis.
Authors:Vujasinovic M, Dugic A, Thiel T, Kjellman A, Yang C, Löhr JM
Institution:Department of Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Huddinge, Karolinska Institute, Stockholm, Sweden. Electronic address: miroslav.vujasinovic@regionstockholm.se.; Department of Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden.
Journal:Pancreatology. 2023 Apr;23(3):294-298. doi: 10.1016/j.pan.2023.03.006. Epub 2023 Mar 22.

7:Prevalence of depression among patients with chronic pancreatitis: A systematic review and meta-analysis.
Authors:Beas R, Riva-Moscoso A, Ribaudo I, Chambergo-Michilot D, Norwood DA, Karkash A, Izquierdo-Veraza D, Montrose J, Ramirez-Rojas M, Montalvan-Sanchez E
Institution:Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: renatobeas@gmail.com.
Journal:Clin Res Hepatol Gastroenterol. 2023 May;47(5):102115. doi: 10.1016/j.clinre.2023.102115. Epub 2023 Mar 26.

8:Advances in acute and chronic pancreatitis.
Authors:Strum WB, Boland CR
Institution:Department of Gastroenterology, Scripps Clinic, La Jolla, CA 92037, United States. williamsonstrum@yahoo.com.; Department of Medicine, University of California San Diego, La Jolla, CA 92037, United States.
Journal:World J Gastroenterol. 2023 Feb 21;29(7):1194-1201. doi: 10.3748/wjg.v29.i7.1194.

9:Burden of bone disease in chronic pancreatitis: A systematic review and meta-analysis.
Authors:Chhoda A, Hernandez-Woodbine MJ, Addo NAA, Nasir SA, Grimshaw A, Gunderson C, Ahmed A, Freedman SD, Sheth SG
Institution:Department of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States. ssheth@bidmc.havard.edu.
Journal:World J Gastroenterol. 2023 Feb 28;29(8):1374-1394. doi: 10.3748/wjg.v29.i8.1374.

10:Position statement on the definition, incidence, diagnosis and outcome of acute on chronic pancreatitis.
Authors:Bouça-Machado T, Bouwense SAW, Brand M, Demir IE, Frøkjær JB, Garg P, Hegyi P, Löhr JM, de-Madaria E, Olesen SS, Pandanaboyana S, Pedersen JB, Rebours V, Sheel A, Singh V, Smith M, Windsor JA, Yadav D, Drewes AM
Institution:Department of Surgery, Aalborg University Hospital, Aalborg, Denmark.; Mech-Sense & Centre for Pancreatic Diseases, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark. Electronic address: amd@rn.dk.
Journal:Pancreatology. 2023 Mar;23(2):143-150. doi: 10.1016/j.pan.2023.01.010. Epub 2023 Jan 25.

11:Long-Term Survival Outcomes after Operative Management of Chronic Pancreatitis: Two Decades of Experience.
Authors:Wilson GC, Turner KM, Delman AM, Wahab S, Ofosu A, Smith MT, Choe KA, Patel SH, Ahmad SA
Institution:From the University of Cincinnati Pancreatic Disease Center, University of Cincinnati College of Medicine, Cincinnati, OH.
Journal:J Am Coll Surg. 2023 Apr 1;236(4):601-610. doi: 10.1097/XCS.0000000000000575. Epub 2023 Mar 15.

12:Smoking Is Associated with Worse Clinical Outcomes in Chronic Pancreatitis.
Authors:Liyen Cartelle A, Bocchino RL, Shah I, Yakah W, Ahmed A, Freedman SD, Kothari DJ, Sheth SG
Institution:Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA. ssheth@bidmc.harvard.edu.
Journal:Dig Dis Sci. 2023 Jun;68(6):2667-2673. doi: 10.1007/s10620-023-07841-4. Epub 2023 Jan 30.

13:Long-term clinical outcomes of a fully covered self-expandable metal stent for refractory pancreatic strictures in symptomatic chronic pancreatitis: An 11-year follow-up study.
Authors:Ko SW, So H, Oh D, Song TJ, Park DH, Lee SS, Seo DW, Lee SK
Institution:Department of Internal Medicine, The Catholic University of Korea, Eunpyeong St. Mary's Hospital, Seoul, South Korea.; Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Journal:J Gastroenterol Hepatol. 2023 Mar;38(3):460-467. doi: 10.1111/jgh.16105. Epub 2023 Jan 18.

14:Incidence and risk of pancreatic cancer in patients with chronic pancreatitis: defining the optimal subgroup for surveillance.
Authors:Kim HS, Gweon TG, Park SH, Kim TH, Kim CW, Chang JH
Institution:Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. wwjjaang@catholic.ac.kr.
Journal:Sci Rep. 2023 Jan 3;13(1):106. doi: 10.1038/s41598-022-26411-8.

15:Role of Intraoperative Coeliac Plexus Neurolysis on Postoperative Pain Management for Chronic Pancreatitis.
Authors:Shahriar S, Khan ZR, Chowdhury MM, Das BC, Ahmed A, Hoque KR, Alam SF
Institution:Dr Shaon Shahriar, Assistant Professor, Hepatobiliary Surgery, Shaheed Suhrawardy Medical College (ShSMC), Dhaka, Bangladesh; E-mail: shaon_s@hotmail.com.
Journal:Mymensingh Med J. 2023 Jan;32(1):90-95.

16:Smoking as the most important risk factor for chronic pancreatitis in the general population.
Authors:Hansen SEJ, Nordestgaard BG, Langsted A
Institution:Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Borgmester Ib Juuls Vej 73, 2730, Herlev, Denmark. anne.langsted.01@regionh.dk.
Journal:Eur J Epidemiol. 2023 Jan;38(1):95-107. doi: 10.1007/s10654-022-00945-7. Epub 2023 Jan 3.

17:Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
Authors:Dugic A, Hagström H, Dahlman I, Rutkowski W, Daou D, Kulinski P, Löhr JM, Vujasinovic M
Institution:Department of Medicine, Huddinge, Karolinska Institute, Stockholm, Sweden.
Journal:United European Gastroenterol J. 2023 Feb;11(1):79-91. doi: 10.1002/ueg2.12344. Epub 2022 Dec 1.

18:Pre-existing, Concurrent/Early-Onset, and Late-Onset Diabetes in Chronic Pancreatitis: Do Outcomes Differ?
Authors:Zuberi SA, Shah I, Bocchino RL, Ahmed A, Freedman SD, Kothari DJ, Sheth SG
Institution:Department of Internal Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Department of Internal Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA. ssheth@bidmc.harvard.edu.
Journal:Dig Dis Sci. 2023 Apr;68(4):1519-1524. doi: 10.1007/s10620-022-07742-y. Epub 2022 Nov 1.

19:Painless chronic pancreatitis: experiences from a high-volume center.
Authors:Vujasinovic M, Asplund E, Kourie M, Guliaieva M, Dugic A, Waldthaler A, Baldaque-Silva F, Löhr JM, Ghorbani P
Institution:Department of Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden.
Journal:Scand J Gastroenterol. 2023 Apr;58(4):417-421. doi: 10.1080/00365521.2022.2137692. Epub 2022 Oct 27.

20:Predictors of 90-day morbidity and mortality after Frey procedure for chronic pancreatitis.
Authors:Ray S, Dhali A, Ansari Z, Gupta A, Mukherjee S, Das S, Das S, Mandal TS, Biswas J, Khamrui S, Dhali GK
Institution:Division of GI Surgery, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244 A. J. C. Bose Road, Kolkata, 700020, West Bengal, India. Electronic address: drsukantaray@yahoo.co.in.; Division of Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244 A. J. C. Bose Road, Kolkata, 700020, West Bengal, India.
Journal:Am J Surg. 2023 Apr;225(4):709-714. doi: 10.1016/j.amjsurg.2022.10.013. Epub 2022 Oct 13.

21:Soft self-expandable metal stent to treat painful pancreatic duct strictures secondary to chronic pancreatitis: a prospective multicenter trial.
Authors:Sherman S, Kozarek RA, Costamagna G, Reddy DN, Tarnasky P, Shah RJ, Slivka A, Fogel E, Watkins J, Delhaye M, Irani SS, Tringali A, Lakhtakia S, Kedia P, Edmundowicz S, Peetermans JA, Rousseau MJ, Devière J
Institution:Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Gastroenterology, Hopital Erasme, Brussels, Belgium.
Journal:Gastrointest Endosc. 2023 Mar;97(3):472-481.e3. doi: 10.1016/j.gie.2022.09.021. Epub 2022 Oct 5.

22:Clinical Course of Medically Managed Patients With Large and Small Duct Chronic Pancreatitis.
Authors:Mahdi MB, Steinkohl E, Singh VK, Drewes AM, Frøkjær JB, Olesen SS
Institution:Centre for Pancreatic Diseases and Mech-Sense, Department of Gastroenterology & Hepatology, Aalborg University Hospital, Aalborg, Denmark.
Journal:Clin Transl Gastroenterol. 2023 Jan 1;14(1):e00537. doi: 10.14309/ctg.0000000000000537.

23:Efficacy and Predictors of Pain Response to Combined Antioxidants in Children with Chronic Pancreatitis.
Authors:Gopan A, Srivastava A, Mathias A, Yachha SK, Jain SK, Mishra P, Sarma MS, Poddar U
Institution:Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, 226014, India.
Journal:Dig Dis Sci. 2023 Apr;68(4):1500-1510. doi: 10.1007/s10620-022-07676-5. Epub 2022 Aug 28.

24:Chronic Pancreatitis in Females is Not Associated With Adverse Pregnancy Outcomes: A Retrospective Analysis.
Authors:Rana A, Sharma S, Qamar S, Zangmo R, Gopi S, Agarwal S, Sharma KA, Singh N, Gunjan D, Saraya A
Institution:Departments of Gastroenterology and Human Nutrition Unit.
Journal:J Clin Gastroenterol. 2023 May-Jun 01;57(5):531-536. doi: 10.1097/MCG.0000000000001711. Epub 2022 Apr 25.

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