Chronic Pancreatitis
September 2021 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Low Bone Mineral Density and Risk for Osteoporotic Fractures in Patients with Chronic Pancreatitis.
Authors:Vujasinovic M, Nezirevic Dobrijevic L, Asplund E, Rutkowski W, Dugic A, Kahn M, Dahlman I, Sääf M, Hagström H, Löhr JM
Institution:Department of Upper Abdominal Diseases, Karolinska University Hospital, 141 86 Stockholm, Sweden. Stockholm, Sweden. Institutet, 141 86 Stockholm, Sweden. Karolinska Institutet, 171 77 Stockholm, Sweden. Stockholm, Sweden. 171 77 Stockholm, Sweden. Stockholm, Sweden. Institutet, 141 86 Stockholm, Sweden.
Journal:Nutrients. 2021 Jul 13;13(7):2386. doi: 10.3390/nu13072386.

2:Multifocal autoimmune pancreatitis: A retrospective study in a single tertiary center of 26 patients with a 20-year literature review.
Authors:Huang XM, Shi ZS, Ma CL
Institution:Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian Province, China. Fuzhou 350005, Fujian Province, China. shizhenshan0206@163.com. Fuzhou 350005, Fujian Province, China.
Journal:World J Gastroenterol. 2021 Jul 21;27(27):4429-4440. doi: 10.3748/wjg.v27.i27.4429.

3:Impact of surgery for chronic pancreatitis on the risk of pancreatic cancer: Untying the Gordian knot.
Authors:Kalayarasan R, Narayanan S, Sahoo J, Mohan P
Institution:Department of Surgical Gastroenterology, JIPMER, Puducherry 605006, India. kalayarasanraja@yahoo.com.
Journal:World J Gastroenterol. 2021 Jul 21;27(27):4371-4382. doi: 10.3748/wjg.v27.i27.4371.

4:Comprehensive review of diagnostic modalities for early chronic pancreatitis.
Authors:Ge QC, Dietrich CF, Bhutani MS, Zhang BZ, Zhang Y, Wang YD, Zhang JJ, Wu YF, Sun SY, Guo JT
Institution:Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China. Switzerland. Anderson Cancer Center, Houston, TX 77030, United States. Shenyang 110004, Liaoning Province, China. Shenyang 110004, Liaoning Province, China. Shenyang 110004, Liaoning Province, China. Shenyang 110004, Liaoning Province, China. Shenyang 110004, Liaoning Province, China. Shenyang 110004, Liaoning Province, China. Shenyang 110004, Liaoning Province, China. guojt@sj-hospital.org.
Journal:World J Gastroenterol. 2021 Jul 21;27(27):4342-4357. doi: 10.3748/wjg.v27.i27.4342.

5:Autoimmune pancreatitis and pancreatic cancer: Epidemiological aspects and immunological considerations.
Authors:Poddighe D
Institution:Department of Medicine, School of Medicine, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
Journal:World J Gastroenterol. 2021 Jul 7;27(25):3825-3836. doi: 10.3748/wjg.v27.i25.3825.

6:Pancreatitis and pancreatic cancer: A case of the chicken or the egg.
Authors:Umans DS, Hoogenboom SA, Sissingh NJ, Lekkerkerker SJ, Verdonk RC, van Hooft JE
Institution:Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, Amsterdam 1105 AZ, The Netherlands. d.s.umans@amsterdamumc.nl. Metabolism, Amsterdam UMC, Amsterdam 1105 AZ, The Netherlands. The Netherlands. Metabolism, Amsterdam UMC, Amsterdam 1105 AZ, The Netherlands. 3430 EM, The Netherlands. Leiden 2333 ZA, The Netherlands.
Journal:World J Gastroenterol. 2021 Jun 21;27(23):3148-3157. doi: 10.3748/wjg.v27.i23.3148.

7:Pain management in chronic pancreatitis incorporating safe opioid practices: Challenge accepted.
Authors:Shah I, Sheth SG, Kothari DJ
Institution:Department of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States. Medical School, Boston, MA 02215, United States. ssheth@bidmc.harvard.edu. United States.
Journal:World J Gastroenterol. 2021 Jun 21;27(23):3142-3147. doi: 10.3748/wjg.v27.i23.3142.

8:Genetic Risk Factors in Early-Onset Nonalcoholic Chronic Pancreatitis: An Update.
Authors:Wertheim-Tysarowska K, Oracz G, Rygiel AM
Institution:Department of Medical Genetics, Institute of Mother and Child, Kasprzaka 17a, 01-211 Warsaw, Poland. Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland. Warsaw, Poland.
Journal:Genes (Basel). 2021 May 20;12(5):785. doi: 10.3390/genes12050785.

9:Hereditary pancreatitis in childhood: course of disease and complications.
Authors:Prommer R, Kienbauer M, Kargl S, Schöfl R
Institution:Department of Gastroenterology and Hepatology, Ordensklinikum Linz-Hospital of the Sisters of Charity, Linz, Austria. Sisters of Charity, Linz, Austria. Linz, Austria. Medicine, Endocrinology, Ordensklinikum Linz-Hospital of the Sisters of Charity, Seilerstätte 4, 4010, Linz, Austria. rainer.schoefl@ordensklinikum.at.
Journal:Wien Klin Wochenschr. 2021 Jul;133(13-14):669-673. doi: 10.1007/s00508-021-01869-0. Epub 2021 Apr 28.

10:Intestinal Dysbiosis and Autoimmune Pancreatitis.
Authors:Yoshikawa T, Watanabe T, Kamata K, Hara A, Minaga K, Kudo M
Institution:Department of Gastroenterology and Hepatology, Kindai University, Faculty of Medicine, Ohno-Higashi, Osaka-Sayama, Japan. Medicine, Ohno-Higashi, Osaka-Sayama, Japan. Medicine, Ohno-Higashi, Osaka-Sayama, Japan. Medicine, Ohno-Higashi, Osaka-Sayama, Japan. Medicine, Ohno-Higashi, Osaka-Sayama, Japan. Medicine, Ohno-Higashi, Osaka-Sayama, Japan.
Journal:Front Immunol. 2021 Mar 23;12:621532. doi: 10.3389/fimmu.2021.621532. eCollection 2021.

11:Diagnostic and therapeutic considerations in biopsy-proven type 2 autoimmune pancreatitis: comparative analysis with biopsy-proven type 1 autoimmune pancreatitis.
Authors:Pattabathula K, Waters PS, Hwang J, Bettington M, Singh M, Bryant RD, Cavallucci DJ, O'Rourke N
Institution:Department of Surgery, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia. Australia. Queensland, Australia. Australia. Australia. Australia. Australia.
Journal:ANZ J Surg. 2021 May;91(5):907-914. doi: 10.1111/ans.16445. Epub 2020 Dec 28.

12:Endoscopic management of local complications of chronic pancreatitis.
Authors:Vila JJ, Bolado F
Institution:Aparato Digestivo, Complejo Hospitalario de Navarra, España.
Journal:Rev Esp Enferm Dig. 2021 Aug;113(8):602-609. doi: 10.17235/reed.2020.7372/2020.

13:Pancreatectomy, Islet Cell Transplantation, and Nutrition Considerations.
Authors:Narayanan S, Bhutiani N, Adamson DT, Jones CM
Institution:Division of Transplantation, Hiram C. Polk Jr. MD Department of Surgery, University of Louisville, Louisville, Kentucky, USA. of Louisville, Louisville, Kentucky, USA. of Louisville, Louisville, Kentucky, USA.
Journal:Nutr Clin Pract. 2021 Apr;36(2):385-397. doi: 10.1002/ncp.10578. Epub 2020 Oct 1.

14:Nutritional management of chronic pancreatitis: A systematic review and meta-analysis of randomized controlled trials.
Authors:Wiese M, Gärtner S, Doller J, Tran QT, Frost F, Bannert K, Jaster R, Berlin P, Valentini L, Meyer F, Metges CC, Lamprecht G, Lerch MM, Aghdassi AA
Institution:Department of Medicine A, University Medicine Greifswald, Greifswald, Germany. Center, Rostock, Germany. Center, Rostock, Germany. Center, Rostock, Germany. Neubrandenburg, Neubrandenburg, Germany. Neubrandenburg, Neubrandenburg, Germany. Animal Biology (FBN), Dummerstorf, Germany. Center, Rostock, Germany.
Journal:J Gastroenterol Hepatol. 2021 Mar;36(3):588-600. doi: 10.1111/jgh.15230. Epub 2020 Sep 22.

15:Morphologic Factors Predict Pain Relief Following Pancreatic Head Resection in Chronic Pancreatitis Description of the Chronic Pancreatitis Pain Relief (CPPR) Score.
Authors:Bachmann K, Melling N, Groteluschen R, Fleischauer A, Reeh M, Ghadban T, Bockhorn M, Izbicki JR
Institution:Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Martinistraße, Hamburg, Germany.
Journal:Ann Surg. 2021 Apr 1;273(4):800-805. doi: 10.1097/SLA.0000000000003439.

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