| | Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.
Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Atrial Fibrillation abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Atrial Fibrillation. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Atrial Fibrillation. You can access the summaries of each article referenced below by simply clicking on the article Title.
We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Atrial Fibrillation every 3 months. Thank you for your ongoing subscription to this publication.
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.
| Authors: | Matusik PT, Heleniak Z, Undas A |
| Institution: | The John Paul II Hospital, Krakow, Poland; Department of Electrocardiology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.; The John Paul II Hospital, Krakow, Poland; Department of Thromboembolic Diseases, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland. | | Journal: | Anatol J Cardiol. 2022 Dec;26(12):857-863. doi: 10.5152/AnatolJCardiol.2022.2426. |
| Authors: | Gómez-Outes A, Suárez-Gea ML, Pérez-Cabeza AI, García-Pinilla JM |
| Institution: | Division of Pharmacology and Clinical Drug Evaluation, Medicines for Human Use, Spanish Agency for Medicines and Medical Devices (AEMPS), Madrid, Spain.; Servicio de Cardiologia, Hospital Universitario Virgen de la Victoria, Instituto de Biomedicina de Malaga (IBIMA), Malaga, Spain. | | Journal: | Expert Opin Pharmacother. 2022 Dec;23(17):1941-1955. doi: 10.1080/14656566.2022.2149323. Epub 2022 Nov 27. |
| Authors: | Mircea AA, Rusu M, Liehn EA, Bucur O |
| Institution: | Victor Babes National Institute of Pathology, 050096 Bucharest, Romania. | | Journal: | Int J Mol Sci. 2022 Oct 20;23(20):12612. doi: 10.3390/ijms232012612. |
| Authors: | Long B, Keim SM, Gottlieb M, Stiell IG |
| Institution: | Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas.; Department of Emergency Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada. | | Journal: | J Emerg Med. 2022 Sep;63(3):467-476. doi: 10.1016/j.jemermed.2022.07.014. Epub 2022 Oct 11. |
| Authors: | Jia X, Yin Z, Zhang W, Du S, Kang J |
| Institution: | Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, 43 North University Road, Zhengzhou City, 450052, Henan Province, China. jiaxd.zzu@163.com.; Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, 43 North University Road, Zhengzhou City, 450052, Henan Province, China. 2455232597@qq.com. | | Journal: | J Transl Med. 2022 Sep 30;20(1):441. doi: 10.1186/s12967-022-03652-9. |
| Authors: | Andrade JG, Deyell MW, Dubuc M, Macle L |
| Institution: | Montreal Heart Institute, Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada. | | Journal: | Expert Rev Med Devices. 2022 Aug;19(8):623-631. doi: 10.1080/17434440.2022.2129008. Epub 2022 Oct 3. |
| Authors: | Ktenopoulos N, Sagris M, Theofilis P, Lionaki S, Rallidis LS |
| Institution: | Internal Medicine Department, Konstantopoulio General Hospital, 14233 Athens, Attica Province, Greece.; Second Department of Cardiology, University General Hospital, 'Attikon', Athens, National and Kapodistrian University of Athens, 11527 Athens, Attica Province, Greece. | | Journal: | Front Biosci (Schol Ed). 2022 Jul 21;14(3):21. doi: 10.31083/j.fbs1403021. |
| Authors: | Jin S, Fu L, Jiang J, Ye X, Liu H, Chen Y, Pu S, Wu S, Xue Y |
| Institution: | Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. | | Journal: | J Interv Cardiol. 2022 Aug 16;2022:6013474. doi: 10.1155/2022/6013474. eCollection 2022. |
| Authors: | Yildiz M, Lavie CJ, Morin DP, Oktay AA |
| Institution: | The Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio, USA.; The Heart and Vascular Institute, Rush University Medical Center, Chicago, Illinois, USA. | | Journal: | Expert Rev Cardiovasc Ther. 2022 Sep;20(9):707-717. doi: 10.1080/14779072.2022.2115357. Epub 2022 Aug 25. |
| Authors: | Segan L, Prabhu S, Kalman JM, Kistler PM |
| Institution: | The Alfred Hospital, Melbourne, Australia; Baker Heart and Diabetes Research Institute, Melbourne, Australia; University of Melbourne, Melbourne, Australia.; The Alfred Hospital, Melbourne, Australia; Baker Heart and Diabetes Research Institute, Melbourne, Australia; University of Melbourne, Melbourne, Australia; Monash University, Melbourne, Australia. Electronic address: peter.kistler@baker.edu.au. | | Journal: | JACC Clin Electrophysiol. 2022 Aug;8(8):1051-1059. doi: 10.1016/j.jacep.2021.12.008. Epub 2022 Feb 23. |
| Authors: | Gonçalves-Teixeira P, Costa T, Fragoso I, Ferreira D, Brandão M, Leite-Moreira A, Sampaio F, Ribeiro J, Fontes-Carvalho R |
| Institution: | Departamento de Cardiologia, Vila Nova de Gaia Hospital Center, Gaia - Portugal. | | Journal: | Arq Bras Cardiol. 2022 Aug;119(2):328-341. doi: 10.36660/abc.20201362. |
| Authors: | Esteve-Pastor MA, Rivera-Caravaca JM, Ruiz-Ortiz M, Muñiz J, Roldán-Rabadán I, Otero D, López-Gálvez R, Cequier Á, Bertomeu-Martínez V, Badimón L, Anguita M, Lip GYH, Marín F |
| Institution: | Department of Cardiology, Hospital Clinico Universitario Virgen de la Arrixaca, Universidad de Murcia, Instituto Murciano de Investigacion Biosanitaria (IMIB-Arrixaca), CIBERCV, Murcia, Spain. | | Journal: | Expert Opin Pharmacother. 2022 Aug;23(12):1457-1465. doi: 10.1080/14656566.2022.2109961. Epub 2022 Aug 12. |
| Authors: | De Potter T, Klaver M, Babkin A, Iliodromitis K, Hocini M, Cox J, Boersma L |
| Institution: | Cardiovascular Centre, OLV Aalst, Aalst, Belgium. Electronic address: tom.de.potter@olvz-aalst.be.; Cardiology Department, St. Antonius Hospital, Nieuwegein, the Netherlands; Cardiology Department, Amsterdam UMC, Amsterdam, the Netherlands. | | Journal: | JACC Clin Electrophysiol. 2022 Aug;8(8):1034-1039. doi: 10.1016/j.jacep.2022.05.017. Epub 2022 Jul 27. |
| Authors: | Reddy YNV, Borlaug BA, Gersh BJ |
| Institution: | Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. | | Journal: | Circulation. 2022 Jul 26;146(4):339-357. doi: 10.1161/CIRCULATIONAHA.122.057444. Epub 2022 Jul 25. |
| Authors: | Sadek MM, Skanes A, Tang ASL |
| Institution: | Arrhythmia Service, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada.; Schulich School of Medicine and Dentistry, Western University, University Hospital, 339 Windermere Road, London, ON, C6-116, Canada. anthonysltang@gmail.com. | | Journal: | Curr Cardiol Rep. 2022 Oct;24(10):1227-1231. doi: 10.1007/s11886-022-01743-z. Epub 2022 Jul 23. |
| Authors: | Giannone ME, Filippini T, Whelton PK, Chiari A, Vitolo M, Boriani G, Vinceti M |
| Institution: | Department of Biomedical, Metabolic and Neural Sciences, Environmental, Genetic and Nutritional Epidemiology Research Center University of Modena and Reggio Emilia Modena Italy. | | Journal: | J Am Heart Assoc. 2022 Jul 19;11(14):e025653. doi: 10.1161/JAHA.122.025653. Epub 2022 Jul 15. |
| Authors: | Archontakis-Barakakis P, Li W, Kalaitzoglou D, Tzelves L, Manolopoulos A, Giannopoulos S, Giamouzis G, Giannakoulas G, Batsidis A, Palaiodimos L, Ntaios G, Lip GYH, Kokkinidis DG |
| Institution: | Northeast Internal Medicine Associates, LaGrange, IN, USA.; Section of Cardiovascular Medicine, Yale University School of Medicine, Yale New Haven Hospital, New Haven, CT, USA. | | Journal: | Br J Clin Pharmacol. 2022 Nov;88(11):4663-4675. doi: 10.1111/bcp.15464. Epub 2022 Aug 15. |
| Authors: | Miraglia V, Bisignani A, Pannone L, Iacopino S, Chierchia GB, de Asmundis C |
| Institution: | Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, European Reference Networks Guard-Heart, Brussels, Belgium. | | Journal: | Expert Rev Med Devices. 2022 May;19(5):431-439. doi: 10.1080/17434440.2022.2096437. Epub 2022 Jul 18. |
| Authors: | Koniari I, Artopoulou E, Velissaris D, Mplani V, Anastasopoulou M, Kounis N, de Gregorio C, Tsigkas G, Karunakaran A, Plotas P, Ikonomidis I |
| Institution: | Department of Cardiology, University Hospital of South Manchester NHS Foundation Trust, Manchester M23 9LT, UK.; Second Cardiology Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece. | | Journal: | Medicina (Kaunas). 2022 May 30;58(6):743. doi: 10.3390/medicina58060743. |
| Authors: | Gunawardene MA, Willems S |
| Institution: | Department of Cardiology and Intensive Care Medicine, Asklepios Hospital St. Georg, Hamburg, Germany. | | Journal: | Europace. 2022 Jun 6;24(Supplement_2):ii22-ii28. doi: 10.1093/europace/euab257. |
| Authors: | Peng TJ, Viscoli C, Khatri P, Wolfe SQ, Bhatt NR, Girotra T, Kamel H, Sheth KN |
| Institution: | Department of Neurology, Yale University School of Medicine, 15 York Street LCI, 1003C, New Haven, CT, 06510, USA. Kevin.sheth@yale.edu. | | Journal: | Drugs. 2022 Jun;82(9):965-977. doi: 10.1007/s40265-022-01729-9. Epub 2022 Jun 3. |
| Authors: | Qu J, Wang Z, Wang S |
| Institution: | Department of Internal Medicine-Cardiovascular, YanTai YuHuangDing Hospital, Yantai, Shandong, China.; Department of Internal Medicine-Cardiovascular, LiaoCheng People's Hospital, No. 67, Dongchang West Road, Liaocheng, 252000, Shandong, China. zwj131378@126.com. | | Journal: | J Cardiothorac Surg. 2022 May 31;17(1):132. doi: 10.1186/s13019-022-01885-9. |
| Authors: | Darby AE |
| Institution: | Department of Medicine, Cardiology Division, University of Virginia Health System: UVA Health, Charlottesville, VA, USA. aed6d@virginia.edu. | | Journal: | Curr Cardiol Rep. 2022 Jul;24(7):793-799. doi: 10.1007/s11886-022-01697-2. Epub 2022 May 24. |
| Authors: | Camm AJ, Naccarelli GV, Mittal S, Crijns HJGM, Hohnloser SH, Ma CS, Natale A, Turakhia MP, Kirchhof P |
| Institution: | Cardiovascular Clinical Academic Group, St George's University of London, London, United Kingdom. Electronic address: jcamm@sgul.ac.uk.; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck, Berlin, Germany; Atrial Fibrillation Network (AFNET), Munster, Germany; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK. | | Journal: | J Am Coll Cardiol. 2022 May 17;79(19):1932-1948. doi: 10.1016/j.jacc.2022.03.337. |
| Authors: | Hanna-Rivero N, Tu SJ, Elliott AD, Pitman BM, Gallagher C, Lau DH, Sanders P, Wong CX |
| Institution: | Centre for Heart Rhythm Disorders, University of Adelaide, Adelaide, Australia. c.wong@adelaide.edu.au. | | Journal: | BMC Cardiovasc Disord. 2022 May 4;22(1):204. doi: 10.1186/s12872-022-02633-6. |
| Authors: | Obeidat M, Burgess M, Lip GYH |
| Institution: | Department of Cardiology, Aintree Hospital, Liverpool, UK.; Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart and Chest Hospital, Liverpool, UK; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address: gregory.lip@liverpool.ac.uk. | | Journal: | Cardiol Clin. 2022 May;40(2):245-258. doi: 10.1016/j.ccl.2021.12.012. |
| Authors: | Dawwas GK, Barnes GD |
| Institution: | Center for Pharmacoepidemiology Research and Training, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. gkdawwas@pennmedicine.upenn.edu.; Division of Cardiovascular Medicine, Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan Health System, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd, Building #14, Room G214, Ann Arbor, MI, 48109, USA. | | Journal: | Curr Cardiol Rep. 2022 Jun;24(6):731-738. doi: 10.1007/s11886-022-01690-9. Epub 2022 Apr 23. |
| Authors: | Linz B, Hertel JN, Jespersen T, Linz D |
| Institution: | Faculty of Health and Medical Sciences, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia; Department of Cardiology, Maastricht University Medical Centre, Maastricht, The Netherlands. Electronic address: dominik.linz@mumc.nl. | | Journal: | Can J Cardiol. 2022 Sep;38(9):1352-1363. doi: 10.1016/j.cjca.2022.04.009. Epub 2022 Apr 15. |
| Authors: | Young LJ, Antwi-Boasiako S, Ferrall J, Wold LE, Mohler PJ, El Refaey M |
| Institution: | The Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, USA.; The Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA; Department of Surgery, Division of Cardiac Surgery, The Ohio State University, Columbus, OH, USA. Electronic address: Mona.elrefaey@osumc.edu. | | Journal: | Life Sci. 2022 Jun 15;299:120529. doi: 10.1016/j.lfs.2022.120529. Epub 2022 Apr 3. |
| Authors: | Nizami H, Su L, Jain R, Jain R |
| Institution: | School of Medicine, American University of Integrative Sciences, #9 5th Avenue Belleville, St. Michael, Barbados.; Penn State Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA. | | Journal: | Future Cardiol. 2022 Jun;18(6):497-506. doi: 10.2217/fca-2021-0086. Epub 2022 Apr 1. |
| Authors: | Lacoste JL, Szymanski TW, Avalon JC, Kabulski G, Kohli U, Marrouche N, Singla A, Balla S, Jahangir A |
| Institution: | Department of Pharmacy, WVU Medicine, 1 Medical Center Drive, Morgantown, WV, 26505, USA. Jordan.Lacoste.m@wvumedicine.org.; Center for Advanced Atrial Fibrillation Therapies at Aurora St. Luke's Medical Center, Milwaukee, WI, 53215, USA. | | Journal: | Am J Cardiovasc Drugs. 2022 Sep;22(5):475-496. doi: 10.1007/s40256-022-00529-6. Epub 2022 Mar 30. |
| Authors: | Yamane T |
| Institution: | Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan. Electronic address: yamanet1@aol.com. | | Journal: | J Cardiol. 2022 Jul;80(1):22-27. doi: 10.1016/j.jjcc.2022.02.005. Epub 2022 Feb 24. |
| Authors: | Magnocavallo M, Vetta G, Trivigno S, Mariani MV, DI Lullo L, Bellasi A, Della Rocca DG, Severino P, Piro A, Giunta G, Quaglione R, Lavalle C |
| Institution: | Department of Cardiovascular, Respiratory, Nephrology, Anesthesiology and Geriatric Sciences, Sapienza University, Rome, Italy.; Department of Cardiovascular, Respiratory, Nephrology, Anesthesiology and Geriatric Sciences, Sapienza University, Rome, Italy - carlo.lavalle@uniroma1.it. | | Journal: | Minerva Cardiol Angiol. 2022 Jun;70(3):393-402. doi: 10.23736/S2724-5683.22.05891-4. Epub 2022 Feb 25. |
| Authors: | Suwa Y, Miyasaka Y, Taniguchi N, Harada S, Nakai E, Shiojima I |
| Institution: | Division of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan. | | Journal: | J Echocardiogr. 2022 Jun;20(2):69-76. doi: 10.1007/s12574-021-00561-6. Epub 2022 Jan 23. |
| Authors: | Erdem G, Esme M, Doğu BB |
| Institution: | London School of Economics and Political Sciences, London, UK.; Department of Internal Medicine, Division of Geriatric Medicine, Hacettepe University, Ankara, Turkey. | | Journal: | Ir J Med Sci. 2022 Dec;191(6):2517-2523. doi: 10.1007/s11845-021-02891-x. Epub 2022 Jan 21. |
| Authors: | Tzoumas A, Nagraj S, Tasoudis P, Arfaras-Melainis A, Palaiodimos L, Kokkinidis DG, Kampaktsis PN |
| Institution: | Aristotle University of Thessaloniki, Thessaloniki 541 24, Greece.; Division of Cardiology, New York University Langone Medical Center, 550 1st Ave, New York, NY, USA. | | Journal: | Cardiovasc Revasc Med. 2022 Jul;40:172-179. doi: 10.1016/j.carrev.2021.12.006. Epub 2021 Dec 16. |
| Authors: | Burashnikov A |
| Institution: | Lankenau Institute for Medical Research, Wynnewood, PA; and. | | Journal: | J Cardiovasc Pharmacol. 2022 Oct 1;80(4):540-546. doi: 10.1097/FJC.0000000000001182. |
| Authors: | Tan X, Wang Z, Wu X, Zhang J, Song Z, Qiu Y, Chen Z, Wang Z, Chen G |
| Institution: | Department of Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, 215006, Jiangsu Province, China. | | Journal: | J Neurol. 2022 May;269(5):2338-2345. doi: 10.1007/s00415-021-10903-0. Epub 2021 Nov 20. |
| Authors: | Lip GYH, Gue Y, Zhang J, Chao TF, Calkins H, Potpara T |
| Institution: | Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address: gregory.lip@liverpool.ac.uk.; School of Medicine, Belgrade University; Cardiology Clinic, Clinical Centre of Serbia, Belgrade, Serbia. | | Journal: | Trends Cardiovasc Med. 2022 Nov;32(8):501-510. doi: 10.1016/j.tcm.2021.10.001. Epub 2021 Oct 5. |
| Authors: | Klamer TA, Bots SH, Neefs J, Tulevski II, Ruijter HMD, Somsen GA, de Groot JR |
| Institution: | Department of Cardiology, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam, The Netherlands. Electronic address: j.r.degroot@amsterdamumc.nl. | | Journal: | Curr Probl Cardiol. 2022 Oct;47(10):100996. doi: 10.1016/j.cpcardiol.2021.100996. Epub 2021 Oct 2. |
| Authors: | Di Biase L, Diaz JC, Zhang XD, Romero J |
| Institution: | Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx 10467, NY, United States. Electronic address: dibbia@gmail.com. | | Journal: | Trends Cardiovasc Med. 2022 Aug;32(6):378-387. doi: 10.1016/j.tcm.2021.07.006. Epub 2021 Jul 28. |
| Authors: | Tsigkas G, Apostolos A, Despotopoulos S, Vasilagkos G, Kallergis E, Leventopoulos G, Mplani V, Davlouros P |
| Institution: | Department of Cardiology, University Hospital of Patras, Patras, Greece. gregtsig@hotmail.com. | | Journal: | Heart Fail Rev. 2022 Jul;27(4):1201-1210. doi: 10.1007/s10741-021-10133-6. Epub 2021 Jul 4. |
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What Our Customers Are Saying... "The MediFocus Guidebook on Atrial Fibrillation has enhanced and clearly explained this condition for me. It has also enabled me to make choices with confidence regarding my treatment. The references in the medical literature section has put me in touch with the research base in this country. Many thanks."
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Seaford, East Sussex
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