Medifocus Guidebook on Sjogren's Syndrome

A Comprehensive Patient Guide to Symptoms, Treatment, Research, and Support

Updated: July 6, 2021
193 Pages


What is Sjogren's Syndrome?

Sjogren's syndrome, also known as sicca syndrome, is a chronic, slowly progressive autoimmune disorder that primarily affects the salivary glands in the mouth that produce saliva and the lacrimal glands in the eyes that produce tears. The syndrome is named after Henrik Sjogren, a Swedish eye doctor who first described this condition in 1933. The major clinical features of Sjogren's syndrome are dry mouth and dry eye, which affects about 90% of patients. Another common finding associated with this disorder is enlargement of one or more glands. As the disease progresses, it can affect other areas of the body including the joints, lungs, kidneys, gastrointestinal tract, and the nervous system that can lead to more serious complications.

Two distinct types of Sjogren's syndrome have been identified:

  1. Primary - Sjogren's syndrome that occurs alone and is not associated with another underlying autoimmune disease; and
  2. Secondary - Sjogren's syndrome that develops in conjunction with another underlying autoimmune disorder such as rheumatoid arthritis, lupus, or scleroderma. About 50% of patients have secondary Sjogren's.

It's been estimated that up to 4 million people in the U.S. are affected by Sjogren's syndrome. The overwhelming majority (over 90%) of Sjogren's patients are women. Although the condition can affect people of any age, including children and the elderly, it is typically diagnosed between the ages of 45 to 55.

Although currently there is no known cure for Sjogren's syndrome, recently a wide range of treatment options have emerged to better control the symptoms of dry mouth and dry eyes and, therefore, improve the quality of life of patients. Ongoing research worldwide will likely lead to additional novel and more effective treatments and, perhaps, even to the discovery of a cure in the near future.

Overcoming the Fear of the Unknown

At, we understand that a diagnosis of Sjogren's syndrome can be a stressful, life-altering event. Like most people who have received this diagnosis, you've probably never heard of Sjogren's syndrome before and are overwhelmed with questions about this condition. Processing the news of your diagnosis can send you on an emotional roller coaster and lead to fear, anxiety, despair, and a feeling that you'll never be able to cope. It can literally disrupt all aspects of your life!

Mental health professionals note that the negative emotional responses that often accompany a diagnosis of a serious or chronic disease/condition stem from the fear and uncertainty of what may lie ahead. This phenomenon is known as "fear of the unknown", which is defined as the tendency to be afraid of something you don't know anything about because of a lack of prior experience or exposure. When it involves a serious health issue, such as Sjogren's syndrome, the underlying cause of fear of the unknown is a lack of prior information about the condition. Without access to accurate, trustworthy information, you can't properly evaluate your situation and you can't devise a plan of action to help you better cope with your condition. As a result, your anxiety level continues to rise from a feeling that you can't control your circumstances.

To overcome the fear and uncertainty that often develops as a consequence of a serious medical diagnosis, psychologists recommend that patients confront their situation directly by doing research about their specific illness and learn as much as they can about their condition. By arming yourself with accurate, reliable information, you'll be in a much better position to take control of your situation and make more informed healthcare decisions. If you're willing to take this step, we're here to help you. That's why we created the Medifocus Guidebook on Sjogren's Syndrome.

Medifocus Guidebook on Sjogren's Syndrome

Over the past decade, advances in both basic and clinical research have led to a more comprehensive understanding of the underlying disease process that causes Sjogren's syndrome that paved the way for the development of improved methods for both the diagnosis and management of patients suffering with this disorder. The Medifocus Guidebook on Sjogren's Syndrome captures and summarizes these advances in knowledge within a single, one-of-a-kind book that you won't find in any other single resource. Organized in a logical, easy to use format, the Guidebook imparts vitally important information that includes the following aspects of Sjogren's syndrome:

  • The current theories about the underlying causes of Sjogren's syndrome.
  • The role of the immune system and autoantibodies in the initiation and progression of Sjogren's syndrome.
  • A detailed review of the classic sicca symptoms of dry mouth and dry eye that are prominent clinical features of Sjogren's syndrome.
  • A comprehensive overview of the systemic manifestations of Sjogren's syndrome that can result from disease progression and its effect on other vital body tissues and organs.
  • A detailed explanation of the specific clinical diagnostic tests and laboratory studies that healthcare providers use to evaluate patients who are suspected as having Sjogren's syndrome.
  • The major diagnostic criteria established by the American College of Rheumatology that must be met in order to confirm a diagnosis of Sjogren's syndrome.
  • An outline of other medical conditions that mimic the symptoms of Sjogren's syndrome and must be ruled out as part of the differential diagnosis.
  • The treatment options for Sjogren's dry mouth, including a detailed review of saliva substitutes, saliva stimulants, and the benefits of adhering to good oral hygiene practices.
  • The treatment options for Sjogren's dry eye, including the role of artificial tears, ophthalmic inserts, lubricating eye ointments, and immunosuppressant medications.
  • An overview of the treatment guidelines recommended for the management of the often debilitating fatigue that affects many patients with Sjogren's syndrome.
  • A detailed discussion of important quality of life issues for patients with Sjogren's syndrome, including its impact on the physical, psychological, social, and economic aspects of living daily with the condition.
  • An extensive bibliography of references from recent medical literature published in reputable journals about Sjogren's syndrome. Includes links to the summaries of all articles.
  • A valuable directory with the names and locations of healthcare professionals*, **medical centers, and research institutions with a specialized focus on patients with Sjogren's syndrome.
  • A listing of organizations and support groups whose purpose is to help patients suffering with Sjogren's syndrome by providing access to additional information, resources, and other services.

More Details about the Sjogren's Syndrome Guidebook

  • Last updated on July 6, 2021. 193 Pages.
  • Available in both PRINT (soft-cover book) and DIGITAL (PDF download) formats, each at a special 20% Discount. The choice is up to you.
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  • With your purchase, you also receive free Guidebook updates for 1-year.
  • The Guidebook comes with our 100% Risk-Free Guarantee.
  • Order online or over the phone by calling us toll-free at 1-800-965-3002 or 1-301-649-9300.
  • For more information, download the Free Guidebook Preview
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Medifocus Guidebook on Sjogren's Syndrome

Updated: July 6, 2021
193 Pages

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What Our Customers Are Saying...

"I wanted to take the time to thank you for our outstanding publication on Sjogren's syndrome. I was highly impressed with the in-depth overview of this condition and the treatment options that are available. As a busy executive with little free time on my hands, I could never have found all of the important information on Sjogren's syndrome that your Guidebook provided. I look forward to reading the updates when they become available."
Reading, Pennsylvania

"My sincere gratitude and appreciation go out to everyone at Medifocus for producing this valuable Guidebook on Sjogren's syndrome. I was diagnosed with Sjogren's 6 years ago and have read a lot about this disorder over the years. Your publication, however, is absolutely the VERY BEST resource I have come across. My husband, who is a physician, also read the Guidebook and was hightly impressed by how thoroughly the information was researched. Keep up the good work!"
Greensboro, North Carolina


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