October 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Spondylolisthesis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Spondylolisthesis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Spondylolisthesis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Spondylolisthesis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:Comparing minimally invasive transforaminal lumbar interbody fusion and posterior lumbar interbody fusion for spondylolisthesis: A STROBE-compliant observational study.
Authors:Zhang D, Mao K, Qiang X
Institution:aPuyang Oilfield General Hospital, Puyang bDepartment of Orthopaedics, Chinese PLA General Hospital (301 Hospital), Beijing, PR China.
Journal:Medicine (Baltimore). 2017 Sep;96(37):e8011. doi: 10.1097/MD.0000000000008011.

2:The Role of the Features of Facet Joint Angle in the Development of Isthmic Spondylolisthesis in Young Male Patients with L5-S1 Isthmic Spondylolisthesis.
Authors:Eroglu A, Carli BA, Pusat S, Simsek H
Institution:Department of Neurosurgery, Haydarpasa Sultan Abdulhamid Education and Research Hospital, Istanbul, Turkey. Electronic address: drahmeteroglu@gmail.com. Education and Research Hospital, Istanbul, Turkey. Hospital, Istanbul, Turkey. Hospital, Istanbul, Turkey.
Journal:World Neurosurg. 2017 Aug;104:709-712. doi: 10.1016/j.wneu.2017.05.006. Epub 2017 May 23.

3:Outcomes of Posterolateral Fusion with and without Instrumentation and of Interbody Fusion for Isthmic Spondylolisthesis: A Prospective Study.
Authors:Endler P, Ekman P, Moller H, Gerdhem P
Institution:1Department of Clinical Science, Intervention and Technology, Karolinska Institutet, and Department of Orthopaedics, Karolinska University Hospital, Stockholm, Sweden 2Department of Clinical Sciences, Karolinska Institutet, Sodersjukhuset, and Department of Orthopaedics, Sodersjukhuset, Stockholm, Sweden.
Journal:J Bone Joint Surg Am. 2017 May 3;99(9):743-752. doi: 10.2106/JBJS.16.00679.

4:Worker's Compensation Status and Outcomes Following Anterior Lumbar Interbody Fusion: Prospective Observational Study.
Authors:Phan K, Davies S, Rao PJ, Mobbs RJ
Institution:NeuroSpine Surgery Research Group, Prince of Wales Private Hospital, Sydney, Australia; University of Sydney, Sydney Medical School, Sydney, Australia; University of New South Wales, Sydney, Australia. Australia; University of New South Wales, Sydney, Australia. Australia; University of New South Wales, Sydney, Australia. Electronic address: ralphmobbs@hotmail.com.
Journal:World Neurosurg. 2017 Jul;103:680-685. doi: 10.1016/j.wneu.2017.04.123. Epub 2017 Apr 27.

5:Descriptive Analysis of Spinal Neuroaxial Injections, Surgical Interventions, and Physical Therapy Utilization for Degenerative Lumbar Spondylolisthesis Within Medicare Beneficiaries from 2000 to 2011.
Authors:Sclafani JA, Constantin A, Ho PS, Akuthota V, Chan L
Institution:*Medstar Georgetown University/National Rehabilitation Hospital, Washington, DC daggerUniversity of Colorado, Denver, CO double daggerThe National Institutes of Health, Bethesda, MD.
Journal:Spine (Phila Pa 1976). 2017 Feb 15;42(4):240-246. doi: 10.1097/BRS.0000000000001724.

6:A Novel Nonpedicular Screw-Based Fixation in Lumbar Spondylolisthesis.
Authors:Chen MH, Chen JY
Institution:Division of Neurosurgery, Department of Surgery, Cathay General Hospital, Taipei, Taiwan; School of Medicine, Catholic Fu-Jen University, New Taipei City, Taiwan. Taiwan; Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Taipei Postal Hospital, Taipei, Taiwan.
Journal:Biomed Res Int. 2017;2017:5619350. doi: 10.1155/2017/5619350. Epub 2017 Jan 10.

7:Degenerative spondylolisthesis: contemporary review of the role of interbody fusion.
Authors:Baker JF, Errico TJ, Kim Y, Razi A
Institution:Department of Spine and Spinal Deformity Surgery, NYU Langone Medical Center Hospital for Joint Diseases, 301 East 17th Street, New York, NY, 10002, USA. joseph.f.baker@gmail.com.
Journal:Eur J Orthop Surg Traumatol. 2017 Feb;27(2):169-180. doi: 10.1007/s00590-016-1885-5. Epub 2016 Nov 25.

8:Increased Segmental Range of Motion Is Correlated With Spondylolisthesis in the Cervical Spine After Laminoplasty.
Authors:Shigematsu H, Kura T, Iwata E, Okuda A, Morimoto Y, Masuda K, Tanaka Y
Institution:Department of Orthopaedic Surgery, Nara Medical University, Nara, Japan.
Journal:Spine (Phila Pa 1976). 2017 Apr 1;42(7):E385-E391. doi: 10.1097/BRS.0000000000001828.

9:Patient-reported and radiographic outcomes of minimally invasive transforaminal lumbar interbody fusion for degenerative spondylolisthesis with or without reduction: A comparative study.
Authors:Fan G, Zhang H, Guan X, Gu G, Wu X, Hu A, Gu X, He S
Institution:Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China. Electronic address: tjhss7418@foxmail.com.
Journal:J Clin Neurosci. 2016 Nov;33:111-118. doi: 10.1016/j.jocn.2016.02.037. Epub 2016 Jul 18.

10:Neurogenic claudication secondary to degenerative spondylolisthesis: is fusion always necessary?
Authors:Kitchen WJ, Mohamed M, Bhojak M, Wilby M
Institution:a Department of Neurosurgery , The Walton Centre for Neurology and Neurosurgery , Liverpool , UK. Liverpool , UK. Liverpool , UK. Liverpool , UK.
Journal:Br J Neurosurg. 2016 Dec;30(6):662-665. Epub 2016 Jul 20.

11:Minimally Invasive Surgery Versus Open Surgery Spinal Fusion for Spondylolisthesis: A Systematic Review and Meta-analysis.
Authors:Lu VM, Kerezoudis P, Gilder HE, McCutcheon BA, Phan K, Bydon M
Institution:*Department of Neurologic Surgery, Mayo Clinic, Rochester, MN daggerNeuro-Informatics Laboratory, Mayo Clinic, Rochester, MN double daggerSydney Medical School, University of Sydney, Australia.
Journal:Spine (Phila Pa 1976). 2017 Feb;42(3):E177-E185. doi: 10.1097/BRS.0000000000001731.

12:Two-Year Comparative Outcomes of MIS Lateral and MIS Transforaminal Interbody Fusion in the Treatment of Degenerative Spondylolisthesis: Part II: Radiographic Findings.
Authors:Isaacs RE, Sembrano JN, Tohmeh AG
Institution:*Department of Neurosurgery, Duke University Medical Centere, Durham, NC daggerUniversity of Minnesota, Minneapolis, MN double daggerMinneapolis Veterans Affairs Health Care Systems, Minneapolis, MN section signNorthwest Orthopaedic Specialists, Spokane, WA.
Journal:Spine (Phila Pa 1976). 2016 Apr;41 Suppl 8:S133-44. doi: 10.1097/BRS.0000000000001472.

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