Sjogren's Syndrome
June 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Sjogren's Syndrome abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Sjogren's Syndrome. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Sjogren's Syndrome. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Sjogren's Syndrome every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Evaluation of a new matrix regenerating agent in patients with Sjogren syndrome and superficial ulcerative keratitis resistant to conventional therapy: A report of 3 cases.
Authors:Fajnkuchen F, Barritault D, Giocanti-Auregan A
Institution:Ophthalmology Department, Avicenne Hospital, DHU Vision and Handicaps, APHP, Paris 13 University, Bobigny. Paris 13 University, Bobigny.
Journal:Medicine (Baltimore). 2018 Mar;97(10):e9935. doi: 10.1097/MD.0000000000009935.

2:Expression of interleukin-17 in primary Sjogren's syndrome and the correlation with disease severity: A systematic review and meta-analysis.
Authors:Zhang LW, Zhou PR, Wei P, Cong X, Wu LL, Hua H
Institution:Department of Oral Medicine, Peking University School and Hospital of Stomatology, Beijing, China.; Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, and Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, China.
Journal:Scand J Immunol. 2018 Apr;87(4):e12649. doi: 10.1111/sji.12649.

3:Dental implants in Sjogren's syndrome patients: A systematic review.
Authors:Almeida D, Vianna K, Arriaga P, Moraschini V
Institution:Brazilian Air Force, Odontoclinica de Aeronautica Santos-Dumont, Department of Implantology, Centro, Rio de Janeiro, Brazil. Dentistry, Centro, Niteroi, Rio de Janeiro, Brazil. Dentistry, Centro, Niteroi, Rio de Janeiro, Brazil.
Journal:PLoS One. 2017 Dec 14;12(12):e0189507. doi: 10.1371/journal.pone.0189507. eCollection 2017.

4:Polyvalent immunoglobulins with vitamin D3 and vitamin B12 in the treatment of Sjogren's syndrome in a vegetarian with stomatitis, glossodynia, xerostomia, and elevated antinuclear antibodies: Case report.
Authors:Cuny C, Vaerst B, Gabrielpillai J, Tahtali A, Balster S, Lissner R, Woodcock BG
Journal:Int J Clin Pharmacol Ther. 2018 Jan;56(1):24-27. doi: 10.5414/CP203143.

5:Oral dryness and Sjogren's: an update.
Authors:Shirlaw PJ, Khan A
Institution:Honorary Reader, Unit of Oral Medicine, Floor 23 Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT. Medicine, Floor 23 Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT.
Journal:Br Dent J. 2017 Nov 10;223(9):649-654. doi: 10.1038/sj.bdj.2017.882.

6:Severe intestinal dysbiosis is prevalent in primary Sjogren's syndrome and is associated with systemic disease activity.
Authors:Mandl T, Marsal J, Olsson P, Ohlsson B, Andreasson K
Institution:Section of Rheumatology, Department of Clinical Sciences Malmo, Lund University, Malmo, Sweden. Thomas.mandl@med.lu.se. gata 32, S-205 02, Malmo, Sweden. Thomas.mandl@med.lu.se. Lund, Sweden. Sweden. Malmo, Sweden. University, Malmo, Sweden. Lund, Sweden.
Journal:Arthritis Res Ther. 2017 Oct 24;19(1):237. doi: 10.1186/s13075-017-1446-2.

7:Primary Sjogren's syndrome: Extraglandular manifestations and hydroxychloroquine therapy.
Authors:Demarchi J, Papasidero S, Medina MA, Klajn D, Chaparro Del Moral R, Rillo O, Martire V, Crespo G, Secco A, Catalan Pellet A, Amitrano C, Crow C, Asnal C, Pucci P, Caeiro F, Benzanquen N, Pirola JP, Mayer M, Zazzetti F, Velez S, Barreira J, Tamborenea N, Santiago L, Raiti L
Institution:Hospital General de Agudos Dr. E. Tornu, Buenos Aires, Argentina. juliademarchireum@gmail.com.
Journal:Clin Rheumatol. 2017 Nov;36(11):2455-2460. doi: 10.1007/s10067-017-3822-3. Epub 2017 Sep 14.

8:Primary Sjogren's syndrome and the risk of acute pancreatitis: a nationwide cohort study.
Authors:Chang CC, Chang YS, Wang SH, Lin SY, Chen YH, Chen JH
Institution:Division of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan. Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. Taiwan. Medical University, Taipei, Taiwan. Taiwan. Taiwan. University, Taipei, Taiwan.
Journal:BMJ Open. 2017 Aug 11;7(8):e014807. doi: 10.1136/bmjopen-2016-014807.

9:Long-term follow-up in primary Sjogren's syndrome reveals differences in clinical presentation between female and male patients.
Authors:Ramirez Sepulveda JI, Kvarnstrom M, Eriksson P, Mandl T, Norheim KB, Johnsen SJ, Hammenfors D, Jonsson MV, Skarstein K, Brun JG, Ronnblom L, Forsblad-d'Elia H, Magnusson Bucher S, Baecklund E, Theander E, Omdal R, Jonsson R, Nordmark G, Wahren-Herlenius M
Institution:Unit of Experimental Rheumatology, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden. Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden. University, Linkoping, Sweden. Hospital, Stavanger, Norway. Hospital, Stavanger, Norway. Bergen, Bergen, Norway. Bergen, Bergen, Norway. University of Bergen, Bergen, Norway. Bergen, Bergen, Norway. Bergen, Bergen, Norway.
Journal:Biol Sex Differ. 2017 Aug 8;8(1):25. doi: 10.1186/s13293-017-0146-6.

10:Salivary gland ultrasonography as a predictor of clinical activity in Sjogren's syndrome.
Authors:Fidelix T, Czapkowski A, Azjen S, Andriolo A, Trevisani VFM
Institution:Department of Evidence-Based Medicine, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP, Brazil. (UNIFESP), Sao Paulo, SP, Brazil.
Journal:PLoS One. 2017 Aug 4;12(8):e0182287. doi: 10.1371/journal.pone.0182287. eCollection 2017.

11:Incidence, mortality, and causes of death in physician-diagnosed primary Sjogren's syndrome in Korea: A nationwide, population-based study.
Authors:Kim HJ, Kim KH, Hann HJ, Han S, Kim Y, Lee SH, Kim DS, Ahn HS
Institution:Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Republic of Korea. Electronic address: ibem.ku@gmail.com.; Department of Public Health, Graduate School, Korea University, Seoul, Republic of Korea; Health Insurance Review and Assessment Service, Republic of Korea.; Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, Republic of Korea. Electronic address: ewhaebm@gmail.com.; Department of Public Health, Graduate School, Korea University, Seoul, Republic of Korea.
Journal:Semin Arthritis Rheum. 2017 Oct;47(2):222-227. doi: 10.1016/j.semarthrit.2017.03.004. Epub 2017 Mar 8.

12:Depression in primary Sjogren's syndrome: a systematic review and meta-analysis.
Authors:Cui Y, Li L, Yin R, Zhao Q, Chen S, Zhang Q, Shen B
Institution:a Department of Nursing , The Second Affiliated Hospital of Nantong University , Nantong , China. Nantong , China.
Journal:Psychol Health Med. 2018 Feb;23(2):198-209. doi: 10.1080/13548506.2017.1339895. Epub 2017 Jun 16.

13:The value of rituximab treatment in primary Sjogren's syndrome.
Authors:Verstappen GM, van Nimwegen JF, Vissink A, Kroese FGM, Bootsma H
Institution:Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: g.m.p.j.verstappen@umcg.nl.; Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Journal:Clin Immunol. 2017 Sep;182:62-71. doi: 10.1016/j.clim.2017.05.002. Epub 2017 May 3.

14:Sjogren's syndrome from the perspective of ophthalmology.
Authors:Kuklinski E, Asbell PA
Institution:Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. NY 10029, United States; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, NY, New York 10029, United States. Electronic address: penny.asbell@mssm.edu.
Journal:Clin Immunol. 2017 Sep;182:55-61. doi: 10.1016/j.clim.2017.04.017. Epub 2017 May 2.

15:Genetics of Sjogren's syndrome.
Authors:Teos LY, Alevizos I
Institution:Sjogren's Syndrome and Salivary Gland Dysfunction Unit, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA. Electronic address: alevizosi@mail.nih.gov.
Journal:Clin Immunol. 2017 Sep;182:41-47. doi: 10.1016/j.clim.2017.04.018. Epub 2017 May 3.

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