Peripheral Neuropathy
October 2017 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Peripheral Neuropathy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Peripheral Neuropathy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Peripheral Neuropathy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Peripheral Neuropathy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Yang-warming method in the treatment of diabetic peripheral neuropathy: an updated systematic review and meta-analysis.
Authors:Panthi S, Jing X, Gao C, Gao T
Institution:Department of Chronic Disease, Liaoning University of Traditional Chinese Medicine, Chongshan East Road No.72, Shenyang, Liaoning, 110032, China.
Journal:BMC Complement Altern Med. 2017 Aug 25;17(1):424. doi: 10.1186/s12906-017-1927-5.

2:Chemotherapy-induced peripheral neuropathy clinical trials: Review and recommendations.
Authors:Gewandter JS, Freeman R, Kitt RA, Cavaletti G, Gauthier LR, McDermott MP, Mohile NA, Mohlie SG, Smith AG, Tejani MA, Turk DC, Dworkin RH
Institution:From the Departments of Anesthesiology (J.S.G., R.A.K., R.H.D.), Biostatistics and Computational Biology (M.P.M.), Neurology (N.A.M., M.A.T.), and Medicine, Hematology/Oncology (S.G.M.), University of Rochester, NY; Department of Neurology (R.F.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; Experimental Neurology Unit (G.C.), School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; Department of Family Medicine and Emergency Medicine (L.R.G.), Faculty of Medicine, Universite Laval, Quebec, Canada; Department of Neurology (A.G.S.), University of Utah, Salt Lake City; and Department of Anesthesiology and Pain Medicine (D.C.T.), University of Washington, Seattle.
Journal:Neurology. 2017 Aug 22;89(8):859-869. doi: 10.1212/WNL.0000000000004272. Epub 2017 Jul 26.

3:Interventions for Neuropathic Pain: An Overview of Systematic Reviews.
Authors:Dosenovic S, Jelicic Kadic A, Miljanovic M, Biocic M, Boric K, Cavar M, Markovina N, Vucic K, Puljak L
Institution:From the Departments of *Anesthesiology and Intensive Care and daggerPediatrics, University Hospital Center Split, Split, Croatia; double daggerAgency for Quality and Accreditation in Health Care and Social Welfare, Zagreb, Croatia; section signLaboratory for Pain Research, Department of Anatomy, Histology and Embryology, University of Split School of Medicine, Split, Croatia; parallelDepartment of Radiology, University Hospital Center Split, Split, Croatia; and paragraph signAgency for Medicinal Products and Medical Devices, Zagreb, Croatia.
Journal:Anesth Analg. 2017 Aug;125(2):643-652. doi: 10.1213/ANE.0000000000001998.

4:Phototherapy for treating foot ulcers in people with diabetes.
Authors:Wang HT, Yuan JQ, Zhang B, Dong ML, Mao C, Hu D
Institution:Burns Centre of PLA, Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 169, Changle West Road, Xi'an, Shanxi Province, China.
Journal:Cochrane Database Syst Rev. 2017 Jun 28;6:CD011979. doi: 10.1002/14651858.CD011979.pub2.

5:Topical antimicrobial agents for treating foot ulcers in people with diabetes.
Authors:Dumville JC, Lipsky BA, Hoey C, Cruciani M, Fiscon M, Xia J
Institution:Division of Nursing, Midwifery & Social Work, School of Health Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK, M13 9PL.
Journal:Cochrane Database Syst Rev. 2017 Jun 14;6:CD011038. doi: 10.1002/14651858.CD011038.pub2.

6:Falls, Functioning, and Disability Among Women With Persistent Symptoms of Chemotherapy-Induced Peripheral Neuropathy.
Authors:Winters-Stone KM, Horak F, Jacobs PG, Trubowitz P, Dieckmann NF, Stoyles S, Faithfull S
Institution:Kerri M. Winters-Stone, Fay Horak, Peter G. Jacobs, Phoebe Trubowitz, Nathan F. Dieckmann, and Sydnee Stoyles, Oregon Health & Science University, Portland, OR; and Sara Faithfull, University of Surrey, Guildford, Surrey, United Kingdom.
Journal:J Clin Oncol. 2017 Aug 10;35(23):2604-2612. doi: 10.1200/JCO.2016.71.3552. Epub 2017 Jun 6.

7:Incidence and risk factors for developing infection in patients presenting with uninfected diabetic foot ulcers.
Authors:Jia L, Parker CN, Parker TJ, Kinnear EM, Derhy PH, Alvarado AM, Huygens F, Lazzarini PA
Institution:Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia. Autonomous Region, China. Technology, Brisbane, Queensland, Australia. Australia. Technology, Brisbane, Queensland, Australia. Queensland, Australia. Brisbane, Queensland, Australia. Australia. Technology, Brisbane, Queensland, Australia. Queensland, Australia. Technology, Brisbane, Queensland, Australia. Queensland, Australia.
Journal:PLoS One. 2017 May 17;12(5):e0177916. doi: 10.1371/journal.pone.0177916. eCollection 2017.

8:Advances in the management of diabetic neuropathy.
Authors:Varkonyi T, Korei A, Putz Z, Martos T, Keresztes K, Lengyel C, Nyiraty S, Stirban A, Jermendy G, Kempler P
Institution:First Department of Medicine, University of Szeged, Szeged, Hungary - Hungary. Hungary.
Journal:Minerva Med. 2017 Oct;108(5):419-437. doi: 10.23736/S0026-4806.17.05257-0. Epub 2017 May 25.

9:Effect of omega-3 supplementation on neuropathy in type 1 diabetes: A 12-month pilot trial.
Authors:Lewis EJH, Perkins BA, Lovblom LE, Bazinet RP, Wolever TMS, Bril V
Institution:From the Department of Nutritional Sciences (E.J.H.L., R.P.B., T.M.S.W.), Faculty of Medicine, University of Toronto; Leadership Sinai Centre for Diabetes (B.A.P., L.E.L.), Mount Sinai Hospital, Toronto; and Ellen and Martin Prosserman Centre for Neuromuscular Diseases (V.B.), Division of Neurology, University Health Network, Toronto, Canada.
Journal:Neurology. 2017 Jun 13;88(24):2294-2301. doi: 10.1212/WNL.0000000000004033. Epub 2017 May 17.

10:Chemotherapy-induced peripheral neuropathy: A current review.
Authors:Staff NP, Grisold A, Grisold W, Windebank AJ
Institution:Department of Neurology, Mayo Clinic, Rochester, MN. Austria.
Journal:Ann Neurol. 2017 Jun;81(6):772-781. doi: 10.1002/ana.24951. Epub 2017 Jun 5.

11:Outcomes after foot surgery in people with a diabetic foot ulcer and a 12-month follow-up.
Authors:Lenselink E, Holloway S, Eefting D
Institution:Wound Expert Clinic, Haaglanden Medical Centre, The Hague, The Netherlands. Medicine, College of Biomedical and Life Sciences, Cardiff, Wales, UK. Netherlands.
Journal:J Wound Care. 2017 May 2;26(5):218-227. doi: 10.12968/jowc.2017.26.5.218.

12:Update on Chemotherapy-Induced Peripheral Neuropathy.
Authors:Cioroiu C, Weimer LH
Institution:Neurological Institute of New York, Columbia University Medical Center, 710 W168th Street, New York, NY, 10032, USA. W168th Street, New York, NY, 10032, USA.
Journal:Curr Neurol Neurosci Rep. 2017 Jun;17(6):47. doi: 10.1007/s11910-017-0757-7.

13:Treatment options for diabetic foot osteomyelitis.
Authors:Senneville E, Robineau O
Institution:a Infectious Diseases Department , Gustave Dron Hospital , Tourcoing , France. Salengro Hospital of Lille , French Reference Center for Osteo-Articular Infections (CRIOAC Lille-Tourcoing) , France. Salengro Hospital of Lille , French Reference Center for Osteo-Articular Infections (CRIOAC Lille-Tourcoing) , France.
Journal:Expert Opin Pharmacother. 2017 Jun;18(8):759-765. doi: 10.1080/14656566.2017.1316375. Epub 2017 May 19.

14:Pharmacotherapy for diabetic peripheral neuropathy pain and quality of life: A systematic review.
Authors:Waldfogel JM, Nesbit SA, Dy SM, Sharma R, Zhang A, Wilson LM, Bennett WL, Yeh HC, Chelladurai Y, Feldman D, Robinson KA
Institution:From the Department of Pharmacy (J.M.W., S.A.N.), The Johns Hopkins Hospital; Department of Health Policy & Management (S.M.D., R.S., A.Z., L.M.W.), Johns Hopkins Bloomberg School of Public Health; Division of General Internal Medicine (W.L.B., K.A.R.) and Department of Physical Medicine & Rehabilitation (D.F.), Johns Hopkins University School of Medicine; Departments of Medicine, Epidemiology, and Oncology (H.-C.Y.), Division of General Internal Medicine, Johns Hopkins University, Baltimore, MD; and Department of Internal Medicine (Y.C.), Morehouse School of Medicine, Atlanta, GA.
Journal:Neurology. 2017 May 16;88(20):1958-1967. doi: 10.1212/WNL.0000000000003882. Epub 2017 Mar 24.

15:Randomized controlled trial of neurofeedback on chemotherapy-induced peripheral neuropathy: A pilot study.
Authors:Prinsloo S, Novy D, Driver L, Lyle R, Ramondetta L, Eng C, McQuade J, Lopez G, Cohen L
Institution:Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. Houston, Texas. Houston, Texas. Iowa. Texas MD Anderson Cancer Center, Houston, Texas. Anderson Cancer Center, Houston, Texas. Houston, Texas.
Journal:Cancer. 2017 Jun 1;123(11):1989-1997. doi: 10.1002/cncr.30649. Epub 2017 Mar 3.

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