Peripheral Neuropathy
January 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Peripheral Neuropathy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Peripheral Neuropathy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Peripheral Neuropathy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Peripheral Neuropathy every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Peripheral neuropathy in the hands of people with diabetes mellitus.
Authors:Ennis SL, Galea MP, O'Neal DN, Dodson MJ
Institution:School of Medicine, University of Notre Dame, Australia. Electronic address: samantha.ennis1@my.nd.edu.au. Parkville, Victoria 3010, Australia. Electronic address: m.galea@unimelb.edu.au. 4th Floor Clinical Sciences Building, Fitzroy, Victoria 3065, Australia. Electronic address: dno@unimelb.edu.au.
Journal:Diabetes Res Clin Pract. 2016 Sep;119:23-31. doi: 10.1016/j.diabres.2016.06.010. Epub 2016 Jun 18.

2:Inflammation as a Therapeutic Target for Diabetic Neuropathies.
Authors:Pop-Busui R, Ang L, Holmes C, Gallagher K, Feldman EL
Institution:Department of Internal Medicine, Division of Metabolism, Metabolism Endocrinology and Diabetes, University of Michigan, 5329 Brehm Tower, 1000 Wall Street, Ann Arbor, MI, 48105, USA. rpbusui@umich.edu. and Diabetes, University of Michigan, 5329 Brehm Tower, 1000 Wall Street, Ann Arbor, MI, 48105, USA. ang@med.umich.edu. Suite 1300 24 Frank Lloyd Wright Drive, PO Box 451, Ann Arbor, MI, 48106-0451, USA. crysholm@med.umich.edu. System, 1500 East Medical Center Dr, SPC 5867, Ann Arbor, MI, 48109, USA. kgallag@med.umich.edu. Place, Ann Arbor, MI, 48109-2200, USA. efeldman@umich.edu.
Journal:Curr Diab Rep. 2016 Mar;16(3):29. doi: 10.1007/s11892-016-0727-5.

3:Diabetic foot risk assessment.
Authors:Woodbury MG
Institution:School of Rehabilitation Therapy, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.
Journal:Diabetes Metab Res Rev. 2016 May;32(4):376-8. doi: 10.1002/dmrr.2784. Epub 2016 Mar 8.

4:A high thyroid stimulating hormone level is associated with diabetic peripheral neuropathy in type 2 diabetes patients.
Authors:Zhao W, Zeng H, Zhang X, Liu F, Pan J, Zhao J, Zhao J, Li L, Bao Y, Liu F, Jia W
Institution:Department of Endocrinology & Metabolism, Shanghai Key Laboratory of Diabetes, Shanghai Jiao-Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Medical Center of Diabetes, Shanghai Key Clinical Center of Metabolic Diseases, Shanghai Institute for Diabetes, Shanghai, China. Electronic address: f-liu@sjtu.edu.cn.; Department of Interventional Radiology, Shanghai Jiao-Tong University Affiliated Sixth People's Hospital, Shanghai, China.; Department of Vascular Surgery, Shanghai Jiao-Tong University Affiliated Sixth People's Hospital, Shanghai, China.; Department of Endocrinology & Metabolism, Shanghai Key Laboratory of Diabetes, Shanghai Jiao-Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Medical Center of Diabetes, Shanghai Key Clinical Center of Metabolic Diseases, Shanghai Institute for Diabetes, Shanghai, China. Electronic address: wpjia@sjtu.edu.cn.
Journal:Diabetes Res Clin Pract. 2016 May;115:122-9. doi: 10.1016/j.diabres.2016.01.018. Epub 2016 Jan 19.

5:Forefoot ulcer risk is associated with foot type in patients with diabetes and neuropathy.
Authors:Molines-Barroso RJ, Lazaro-Martinez JL, Aragon-Sanchez FJ, Alvaro-Afonso FJ, Garcia-Morales E, Garcia-Alvarez Y
Institution:Unidad de Pie Diabetico, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), Madrid, Spain. Electronic address: rauljmolines@hotmail.com.; Unidad de Pie Diabetico, Hospital La Paloma, Las Palmas de Gran Canaria, Spain.
Journal:Diabetes Res Clin Pract. 2016 Apr;114:93-8. doi: 10.1016/j.diabres.2016.01.008. Epub 2016 Jan 14.

6:Current concepts of Charcot foot in diabetic patients.
Authors:La Fontaine J, Lavery L, Jude E
Institution:UT Southwestern Medical Center, Department of Plastic Surgery, Dallas, TX, USA. Electronic address: Javier.lafontaine@utsouthwestern.edu.
Journal:Foot (Edinb). 2016 Mar;26:7-14. doi: 10.1016/j.foot.2015.11.001. Epub 2015 Nov 25.

7:Diabetic foot infections: recent literature and cornerstones of management.
Authors:Uckay I, Gariani K, Dubois-Ferriere V, Suva D, Lipsky BA
Institution:aService of Infectious Diseases bOrthopedic Surgery Service cService of Diabetology and Endocrinology, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Switzerland dDivision of Medical Sciences, University of Oxford, Oxford, UK.
Journal:Curr Opin Infect Dis. 2016 Apr;29(2):145-52. doi: 10.1097/QCO.0000000000000243.

8:Efficacy and safety of prostaglandin E1 plus lipoic acid combination therapy versus monotherapy for patients with diabetic peripheral neuropathy.
Authors:Jiang DQ, Li MX, Ma YJ, Wang Y, Wang Y
Institution:Department of Pharmacy, Zhujiang Hospital of Southern Medical University, Industrial Road No. 253, Haizhu District, Guangzhou 510282, China; Cultivation Base for Key Laboratory of Conservation and Utilization of Rare and Economic Species at Southeast Guangxi, Yulin Normal University, Yulin, China; Department of Biopharmaceutical, School of Life Science and Technology, Yulin Normal University, Yulin, China.; Department of Pharmacy, Zhujiang Hospital of Southern Medical University, Industrial Road No. 253, Haizhu District, Guangzhou 510282, China. Electronic address: yongwh2005@hotmail.com.
Journal:J Clin Neurosci. 2016 May;27:8-16. doi: 10.1016/j.jocn.2015.07.028. Epub 2016 Feb 3.

9:National Cancer Institute-supported chemotherapy-induced peripheral neuropathy trials: outcomes and lessons.
Authors:Majithia N, Temkin SM, Ruddy KJ, Beutler AS, Hershman DL, Loprinzi CL
Institution:Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. majithia.neil@mayo.edu. Prevention, National Cancer Institute, 9609 Medical Center Drive, Bethesda, MD, 20892, USA. 55905, USA. 55905, USA. Health, Columbia University College of Physicians and Surgeons, Herbert Irving Comprehensive Cancer Center, Columbia University, Columbia University College of Physicians and Surgeons, New York Presbyterian Hospital, 161 Fort Washington Ave #1068, New York, NY, 10032, USA. 55905, USA.
Journal:Support Care Cancer. 2016 Mar;24(3):1439-47. doi: 10.1007/s00520-015-3063-4. Epub 2015 Dec 19.

10:Small and large fiber neuropathy in those with type 1 and type 2 diabetes: a 5-year follow-up study.
Authors:Loseth S, Stalberg EV, Lindal S, Olsen E, Jorde R, Mellgren SI
Institution:Department of Neurology and Neurophysiology, University Hospital of North Norway, Tromso, Norway. Sweden. Norway. Norway. Tromso, Norway.
Journal:J Peripher Nerv Syst. 2016 Mar;21(1):15-21. doi: 10.1111/jns.12154.

11:Management of critical limb ischemia in the patient with diabetes.
Authors:Forsythe RO, Hinchliffe RJ
Institution:Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, Edinburgh, UK - rhinchli@sgul.ac.uk.
Journal:J Cardiovasc Surg (Torino). 2016 Apr;57(2):273-81. Epub 2015 Dec 2.

12:Risk factors for major amputation in hospitalised diabetic foot patients.
Authors:Namgoong S, Jung S, Han SK, Jeong SH, Dhong ES, Kim WK
Institution:Department of Plastic Surgery, Korea University College of Medicine, Seoul, South Korea. Korea. Korea. Korea. Korea. Korea.
Journal:Int Wound J. 2016 Mar;13 Suppl 1:13-9. doi: 10.1111/iwj.12526. Epub 2015 Oct 19.

13:Chemotherapy-induced peripheral neuropathy after neoadjuvant or adjuvant treatment of breast cancer: a prospective cohort study.
Authors:Pereira S, Fontes F, Sonin T, Dias T, Fragoso M, Castro-Lopes JM, Lunet N
Institution:Portuguese Institute of Oncology of Porto, Rua Dr. Antonio Bernardino de Almeida, 4200-075, Porto, Portugal. n 135, 4050-600, Porto, Portugal. n 135, 4050-600, Porto, Portugal. Faculty of Medicine, University of Porto, Al. Prof. Hernani Monteiro, 4200-319, Porto, Portugal. 4200-075, Porto, Portugal. 4200-075, Porto, Portugal. 4200-075, Porto, Portugal. Prof. Hernani Monteiro, 4200-319, Porto, Portugal. Campo Alegre, n 823, 4150-180, Porto, Portugal. n 135, 4050-600, Porto, Portugal. nlunet@med.up.pt. Faculty of Medicine, University of Porto, Al. Prof. Hernani Monteiro, 4200-319, Porto, Portugal. nlunet@med.up.pt.
Journal:Support Care Cancer. 2016 Apr;24(4):1571-81. doi: 10.1007/s00520-015-2935-y. Epub 2015 Sep 18.

14:People with diabetic peripheral neuropathy display a decreased stepping accuracy during walking: potential implications for risk of tripping.
Authors:Handsaker JC, Brown SJ, Bowling FL, Marple-Horvat DE, Boulton AJ, Reeves ND
Institution:School of Healthcare Science, Manchester Metropolitan University, Manchester, UK.
Journal:Diabet Med. 2016 May;33(5):644-9. doi: 10.1111/dme.12851. Epub 2015 Aug 20.

15:Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy Using an NSAID for Other Pain Conditions: A Double-Blind Crossover Study.
Authors:Raskin P, Huffman C, Yurkewicz L, Pauer L, Scavone JM, Yang R, Parsons B
Institution:*Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX daggerMeridien Research, Tampa, FL double daggerPfizer Inc., Groton, CT section signPfizer Inc., New York, NY.
Journal:Clin J Pain. 2016 Mar;32(3):203-10. doi: 10.1097/AJP.0000000000000254.

16:Topical Citrullus colocynthis (bitter apple) extract oil in painful diabetic neuropathy: A double-blind randomized placebo-controlled clinical trial.
Authors:Heydari M, Homayouni K, Hashempur MH, Shams M
Institution:Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Sciences, Shiraz, Iran. Iran. University of Medical Sciences, Shiraz, Iran.
Journal:J Diabetes. 2016 Mar;8(2):246-52. doi: 10.1111/1753-0407.12287. Epub 2015 Jun 29.

17:Diabetic foot infection treatment and care.
Authors:Cigna E, Fino P, Onesti MG, Amorosi V, Scuderi N
Institution:Department of Plastic and Reconstructive Surgery, 'Sapienza' University, Viale del Policlinico 155, 00161, Rome, Italy.
Journal:Int Wound J. 2016 Apr;13(2):238-42. doi: 10.1111/iwj.12277. Epub 2014 Apr 14.

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What Our Customers Are Saying...

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"I recently purchased your MediFocus Guidebook on Peripheral Neuropathy and found the information quite helpful in making decisions about the direction I wanted to take in dealing with my condition. Even after meeting with a Neurologist and being tested, I had many questions that he was unable to answer. We all have to take control of our own health care and the MediFocus Guidebook is a great tool for doing that."
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