Hereditary Hemochromatosis
February 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Hereditary Hemochromatosis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Hereditary Hemochromatosis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Hereditary Hemochromatosis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Hereditary Hemochromatosis every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Proton Pump Inhibitors Decrease Phlebotomy Need in HFE Hemochromatosis: Double-Blind Randomized Placebo-Controlled Trial.
Authors:Vanclooster A, van Deursen C, Jaspers R, Cassiman D, Koek G
Institution:Department of Gastroenterology-Hepatology and Metabolic Center, University Hospital Leuven, Belgium. Zuyderland Medical Center, Heerlen, The Netherlands; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht UMC+, The Netherlands. Netherlands. Hospital Leuven, Belgium. Maastricht UMC+, The Netherlands; Nutrition and Translational Research in Metabolism (NUTRIM), University Maastricht, The Netherlands; Department of Surgery, University Hospital of the RWTH, Aachen, Germany. Electronic address: gh.koek@mumc.nl.
Journal:Gastroenterology. 2017 Sep;153(3):678-680.e2. doi: 10.1053/j.gastro.2017.06.006. Epub 2017 Jun 15.

2:Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron.
Authors:Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E
Institution:Molecular, Cellular, and Integrative Physiology Graduate Program and. Los Angeles (UCLA), Los Angeles, CA. for Molecular Medicine, University of Oxford, Oxford, United Kingdom. Los Angeles (UCLA), Los Angeles, CA. Los Angeles (UCLA), Los Angeles, CA. Finland; and. Los Angeles (UCLA), Los Angeles, CA. Los Angeles (UCLA), Los Angeles, CA. Los Angeles (UCLA), Los Angeles, CA. Los Angeles (UCLA), Los Angeles, CA.
Journal:Blood. 2017 Jul 20;130(3):245-257. doi: 10.1182/blood-2017-03-772715. Epub 2017 May 2.

3:Iron Overload in the Liver of 2 Children: Nonalcoholic Steatohepatitis and Juvenile Hemochromatosis.
Authors:Unlusoy Aksu A, Caleffi A, Pietrangelo A, Sari S, Egritas Gurkan O, Demirtas Z, Yilmaz G, Dalgic B
Institution:Departments of *Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition double daggerPathology, Gazi University Faculty of Medicine, Ankara, Turkey dagger"Mario Coppo" Liver Research Center, Division of Internal Medicine 2 and Center for Hemochromatosis, University Hospital of Modena, Modena, Italy.
Journal:J Pediatr Hematol Oncol. 2017 Aug;39(6):466-469. doi: 10.1097/MPH.0000000000000752.

4:Movement Disorders Associated With Hemochromatosis.
Authors:Kumar N, Rizek P, Sadikovic B, Adams PC, Jog M
Institution:1Department of Clinical Neurological Sciences,Western University,London,ON,Canada. University,London,ON,Canada. University,London,ON,Canada. University,London,ON,Canada. University,London,ON,Canada.
Journal:Can J Neurol Sci. 2016 Nov;43(6):801-808. doi: 10.1017/cjn.2016.286.

5:Hyperferritinemia increases the risk of hyperuricemia in HFE-hereditary hemochromatosis.
Authors:Flais J, Bardou-Jacquet E, Deugnier Y, Coiffier G, Perdriger A, Chales G, Ropert M, Loreal O, Guggenbuhl P
Institution:Rheumatology Department, Rennes University Hospital, 16, bd de Bulgarie, 35203 Rennes, France. Electronic address: jeremyflais@gmail.com.; INSERM UMR 991, 35000 Rennes, France; University Rennes 1, Medicine Faculty, 35043 Rennes, France; Reference Centre for Rare Genetic Iron Overload Disorders, Clinic for Liver Disorders, Rennes University Hospital, Pontchaillou Hospital, 2 rue Henri Le Guilloux, 35033 Rennes, France.; Rheumatology Department, Rennes University Hospital, 16, bd de Bulgarie, 35203 Rennes, France; University Rennes 1, Medicine Faculty, 35043 Rennes, France.; INSERM UMR 991, 35000 Rennes, France; Reference Centre for Rare Genetic Iron Overload Disorders, Clinic for Liver Disorders, Rennes University Hospital, Pontchaillou Hospital, 2 rue Henri Le Guilloux, 35033 Rennes, France.; Rheumatology Department, Rennes University Hospital, 16, bd de Bulgarie, 35203 Rennes, France; INSERM UMR 991, 35000 Rennes, France; University Rennes 1, Medicine Faculty, 35043 Rennes, France.
Journal:Joint Bone Spine. 2017 May;84(3):293-297. doi: 10.1016/j.jbspin.2016.05.020. Epub 2016 Sep 19.

6:Night sweats: it may be hemochromatosis.
Authors:Murday HK, Rusli FD, Blandy C, Vollenhoven B
Institution:a Final Year Medical Student , Monash University , Clayton Campus , Victoria , Australia ; Medical Centre , Clayton , Victoria , Australia ; Monash University , Monash IVF , Clayton , Victoria , Australia.
Journal:Climacteric. 2016 Aug;19(4):406-8. doi: 10.1080/13697137.2016.1191461. Epub 2016 Jun 14.

7:Haemochromatosis.
Authors:Powell LW, Seckington RC, Deugnier Y
Institution:Centre for the Advancement of Clinical Research, Royal Brisbane and Women's Hospital, Brisbane, The University of Queensland, Brisbane, Australia. Electronic address: lawrie.powell@qimrberghofer.edu.au. Brisbane, Australia.
Journal:Lancet. 2016 Aug 13;388(10045):706-16. doi: 10.1016/S0140-6736(15)01315-X. Epub 2016 Mar 12.

For a FREE PREVIEW of the Medifocus Guidebook on Hereditary Hemochromatosis click here

To purchase a copy of the COMPLETE Medifocus Guidebook on Hereditary Hemochromatosis click here

To subscribe to additional FREE Medifocus Digest Alert on other disease/condition areas click here

  
Get the Medifocus Guidebook on Hereditary Hemochromatosis...
at a Special 20% Discount


Medifocus Guidebook on Hereditary Hemochromatosis

Updated: January 15, 2018
126 Pages

This one of a kind Guidebook offers:

  • Answers to your critical health questions including the latest treatments, clinical trials, and expert research.
     
  • High Quality, Professional level information you can trust and understand culled from the latest peer-reviewed journals.
     
  • Timely, up to date content with free guidebook updates for 1 year.
     
  • A unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks.
     
  • Over 130,000 Guidebooks Sold
     
  • 100% Risk Free Money Back Guarantee



ORDER THE GUIDEBOOK

The Medifocus Guidebook on Hereditary Hemochromatosis is available in the following two convenient formats:

PRINTED GUIDEBOOK

Soft-cover book that is available for immediate shipping via either U.S. Priority Mail or International AirMail (outside the U.S.).

  • Regular List Price = $36.95
  • Less 20% Discount = - $7.40
  • Discounted Price = $29.55(excluding shipping & handling)

Order the Printed Guidebook

DIGITAL GUIDEBOOK

Available for immediate download as a PDF document.

  • Regular List Price = $27.95
  • Less 20% Discount = - $5.60
  • Discounted Price = $22.35

Order the Digital Guidebook



Order by Phone

Call Toll Free in the U.S.
1-800-965-3002

From Outside the U.S.
1-301-649-9300

You can also receive a 20% discount when you order your Guidebook by phone.

To receive your 20% discount, simply mention the Discount Coupon Code below to the customer service representative taking your order.

Discount Coupon Code for
Phone Orders

HH92855883

Coupon Expires: March 19, 2018



What Our Customers Are Saying...

"The MediFocus Guidebook on Hereditary Hemochromatosis was not only extremely informative and well-written but it also explained the genetic aspects of this condition in a way that can be readily understood even by people who donít have a medical or scientific background. I was pleased to learn that so much research is ongoing worldwide to try to better understand the causes of this condtion and, hopefully, come up with a way to prevent this disorder from happening in the first place."
S.D.R.
Perth Amboy, New Jersey


"Your Guidebook on Hereditary Hemochromatosis contains a wealth of information that has helped our family answer many of the questions we had about this relatively obscure genetic disease. The Guidebook allowed us to fully understand the disease and know what to ask...and who to ask to additional information."
D.J.
St. Joseph, Missouri



  
Medifocus Digest Alert is published monthly by Medifocus, Inc.
6810 Park Heights Avenue, Suite C5, Baltimore, MD 21215 USA
Copyright © 2013 Medifocus, Inc. All rights reserved.