Carcinoid Tumors
February 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Carcinoid Tumors abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Carcinoid Tumors. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Carcinoid Tumors. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Carcinoid Tumors every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Efficacy and safety of long-acting pasireotide or everolimus alone or in combination in patients with advanced carcinoids of the lung and thymus (LUNA): an open-label, multicentre, randomised, phase 2 trial.
Authors:Ferolla P, Brizzi MP, Meyer T, Mansoor W, Mazieres J, Do Cao C, Lena H, Berruti A, Damiano V, Buikhuisen W, Gronbaek H, Lombard-Bohas C, Grohe C, Minotti V, Tiseo M, De Castro J, Reed N, Gislimberti G, Singh N, Stankovic M, Oberg K, Baudin E
Institution:Department of Medical Oncology, Multidisciplinary NET Group, Umbria Regional Cancer Network and University of Perugia, Perugia, Italy. Electronic address: pferolla@gmail.com. London, London, UK. UK. Netherlands. Denmark. France.
Journal:Lancet Oncol. 2017 Dec;18(12):1652-1664. doi: 10.1016/S1470-2045(17)30681-2. Epub 2017 Oct 23.

2:Two-Stage Surgery Without Parenchyma Resection for Endobronchial Carcinoid Tumor.
Authors:Pikin O, Ryabov A, Sokolov V, Glushko V, Kolbanov K, Telegina L, Amiraliev A, Barmin V
Institution:Department of Thoracic Surgery, P. A. Hertzen Research Institute of Oncology, Moscow, Russia. Electronic address: pikin_ov@mail.ru. Oncology, Moscow, Russia. Russia. Moscow, Russia. Moscow, Russia. Russia. Moscow, Russia. Moscow, Russia.
Journal:Ann Thorac Surg. 2017 Dec;104(6):1846-1851. doi: 10.1016/j.athoracsur.2017.06.050. Epub 2017 Oct 17.

3:Telotristat ethyl: proof of principle and the first oral agent in the management of well-differentiated metastatic neuroendocrine tumor and carcinoid syndrome diarrhea.
Authors:Masab M, Saif MW
Institution:Albert Einstein Medical Center, Philadelphia, PA, USA. Experimental Therapeutics, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Boston, MA, 02111, USA. wsaif@tuftsmedicalcenter.org.
Journal:Cancer Chemother Pharmacol. 2017 Dec;80(6):1055-1062. doi: 10.1007/s00280-017-3462-y. Epub 2017 Oct 19.

4:Distinctive pathological and clinical features of lung carcinoids with high proliferation index.
Authors:Marchio C, Gatti G, Massa F, Bertero L, Filosso P, Pelosi G, Cassoni P, Volante M, Papotti M
Institution:Department of Medical Sciences, University of Turin, Via Giuseppe Verdi, 8, 10124, Turin, Italy. caterina.marchio@unito.it. 7, 10126, Turin, Italy. caterina.marchio@unito.it. Italy. 7, 10126, Turin, Italy. 10124, Turin, Italy. 7, 10126, Turin, Italy. 10124, Turin, Italy. Festa del Perdono, 7, I-20122, Milan, Italy. Group, Milan, Italy. 10124, Turin, Italy. 7, 10126, Turin, Italy. Italy. Italy. 7, 10126, Turin, Italy. Italy.
Journal:Virchows Arch. 2017 Dec;471(6):713-720. doi: 10.1007/s00428-017-2177-0. Epub 2017 Jun 19.

5:Carcinoid heart disease.
Authors:Hassan SA, Banchs J, Iliescu C, Dasari A, Lopez-Mattei J, Yusuf SW
Institution:Department of Cardiology, Division of Medicine, MD Anderson Cancer Center, Houston, Texas, USA.; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, Texas, USA.
Journal:Heart. 2017 Oct;103(19):1488-1495. doi: 10.1136/heartjnl-2017-311261. Epub 2017 Jun 8.

6:Primary Pulmonary Carcinoid Tumor: A Long-term Single Institution Experience.
Authors:Herde RF, Kokeny KE, Reddy CB, Akerley WL, Hu N, Boltax JP, Hitchcock YJ
Institution:University of Utah School of Medicine. Institute, University of Utah, Salt Lake City, UT.
Journal:Am J Clin Oncol. 2018 Jan;41(1):24-29. doi: 10.1097/COC.0000000000000221.

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What Our Customers Are Saying...

"The MediFocus Guidebook on Carcinoid Tumors helped me prepare for my operation. It was reassuring to be able to communicate with my surgeon and the consulting doctors having knowledge about my condition."
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