Current Status and Progress in the Treatment of Lower Limb Lymphedema After Treatment of Gynecological Oncology

Lymphat Res Biol. 2022 Jun;20(3):308-314. doi: 10.1089/lrb.2021.0035. Epub 2021 Oct 25.

Abstract

Purpose: To discuss the status and progress of treatment of lower limb lymphedema (LLL) after gynecological cancer treatment. Common gynecological malignancies include endometrial cancer, cervical cancer, ovarian cancer, and vulvar cancer. LLL is one of the common complications after gynecological cancer treatment. LLL is one of the common complications after gynecological cancer treatment, which seriously affects patients' quality of life. Methods: We searched the Medline database for literature on LLL after gynecological oncology treatment, reviewed the incidence and risk factors for LLL in different gynecological malignancies, and summarized advances in the prevention and treatment of LLL after gynecological malignancy treatment. Finally, we review data-based approaches for the treatment of LLL and discuss experimental therapies currently in development. Results: Treatment of LLL is usually combined, conservative, and surgical. Complete decongestive therapy is the gold standard for the treatment of LLL. Prevention and treatment of lymphedema of the lower extremities are important for patients with gynecological cancers. Conclusion: Clinicians should be aware of the prevention and treatment of LLL, with a precise diagnosis and effective intervention at an early stage to delay its progression and improve patients' quality of life.

Keywords: complete decongestive therapy; gynecological oncology; lymphedema.

Publication types

  • Review

MeSH terms

  • Female
  • Genital Neoplasms, Female* / complications
  • Genital Neoplasms, Female* / therapy
  • Humans
  • Lower Extremity
  • Lymph Node Excision / adverse effects
  • Lymphedema* / diagnosis
  • Lymphedema* / etiology
  • Lymphedema* / therapy
  • Quality of Life