Superficial margins in skin sparing and nipple sparing mastectomies for DCIS: A margin of potential concern

Trine Tramm; Peer Christiansen; Birgitte Vrou Offersen; Karen Berenth Madsen; Philip Poortmans; Orit Kaidar-Person

doi:10.1016/j.radonc.2021.06.018

Superficial margins in skin sparing and nipple sparing mastectomies for DCIS: A margin of potential concern

Radiother Oncol. 2021 Aug:161:177-182. doi: 10.1016/j.radonc.2021.06.018. Epub 2021 Jun 15.

Authors

Trine Tramm¹, Peer Christiansen², Birgitte Vrou Offersen³, Karen Berenth Madsen⁴, Philip Poortmans⁵, Orit Kaidar-Person⁶

Affiliations

¹ Department of Pathology, Aarhus University Hospital, Denmark. Electronic address: tramm@oncology.au.dk.
² Department of Plastic and Breast Surgery, Aarhus University Hospital, Denmark.
³ Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark.
⁴ Department of Radiology, Aarhus University Hospital, Denmark.
⁵ Iridium Netwerk, Wilrijk-Antwerp, Belgium; University of Antwerp, Faculty of Medicine and Health Sciences, Wilrijk-Antwerp, Belgium.
⁶ Breast Cancer Radiation Therapy Unit, Sheba Medical Center, Ramat Gan, Israel; GROW-School for Oncology and Developmental Biology or GROW (Maastro), Maastricht University, Maastricht, The Netherlands.

PMID: 34139212
DOI: 10.1016/j.radonc.2021.06.018

Abstract

Skin-sparing and nipple-sparing mastectomies with immediate reconstruction for breast cancer are increasing. The superficial fascia is considered a natural border and the superficial margin may not be evaluated. We emphasize the need for reporting of the superficial margin status in these procedures to obtain valid information on its association with local recurrence risks.

Keywords: DCIS; Nipple sparing mastectomy; Resection margin; Skin sparing mastectomy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Breast Neoplasms* / surgery
Carcinoma, Intraductal, Noninfiltrating* / surgery
Female
Humans
Mammaplasty*
Mastectomy
Neoplasm Recurrence, Local / prevention & control
Nipples / surgery
Retrospective Studies