Atrial Fibrillation in Heart Failure: Focus on Antithrombotic Management

Heart Fail Clin. 2020 Jan;16(1):107-120. doi: 10.1016/j.hfc.2019.08.007.

Abstract

Heart failure (HF) and atrial fibrillation (AF), increasingly common in the aging population, are closely related and commonly found together. This article explores the relationship between AF and HF and the thromboembolic effect of these diseases. Morbidity and mortality are increased when the 2 conditions are seen together. Stroke risks are significant with AF and all subtypes of HF. This article suggests that all patients with AF and HF should be considered for anticoagulation. Current evidence suggests that non-vitamin K antagonist oral anticoagulants are effective and safe in AF and HF in comparison with warfarin.

Keywords: Anticoagulation; Atrial fibrillation; Direct oral anticoagulant; Heart failure; NOAC.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Atrial Fibrillation / complications
  • Atrial Fibrillation / drug therapy*
  • Fibrinolytic Agents / therapeutic use*
  • Heart Failure / complications*
  • Heart Failure / drug therapy
  • Humans
  • Stroke / etiology
  • Stroke / prevention & control*

Substances

  • Fibrinolytic Agents