▼ Safinamide for Parkinson's disease

Drug Ther Bull. 2018 May;56(5):54-57. doi: 10.1136/dtb.2018.5.0623.

Abstract

▼ Safinamide (Xadago - Zambon S.p.A) is a monoamine-oxidase B (MAO-B) inhibitor licensed as add-on therapy for people with idiopathic Parkinson's disease who are experiencing motor fluctuations with levodopa.1 Currently there is no cure for Parkinson's disease and drugs are used to reduce motor symptoms and improve daily activities.2,3 Here, we review the evidence for this MAO-B inhibitor.

Publication types

  • Review

MeSH terms

  • Alanine / analogs & derivatives*
  • Alanine / therapeutic use
  • Benzylamines / therapeutic use*
  • Drug Therapy, Combination
  • Dyskinesia, Drug-Induced / complications
  • Dyskinesia, Drug-Induced / drug therapy*
  • Humans
  • Levodopa / adverse effects*
  • Monoamine Oxidase Inhibitors / therapeutic use
  • Parkinson Disease / complications
  • Parkinson Disease / drug therapy*

Substances

  • Benzylamines
  • Monoamine Oxidase Inhibitors
  • Levodopa
  • safinamide
  • Alanine