Herbal Prescriptions and Medicinal Herbs for Parkinson-Related Rigidity in Korean Medicine: Identification of Candidates Using Text Mining

J Altern Complement Med. 2018 Jul;24(7):733-740. doi: 10.1089/acm.2017.0387. Epub 2018 Mar 27.

Abstract

Background: Dongeuibogam (DongYiBaoGian), one of the most important books in Korean medicine, comprises a comprehensive summary of all traditional medicines of North-East Asia before the 17th century. This medicinal literature was mined to establish a list of candidate herbs to treat Parkinson-related rigidity.

Methods: A systematic search for terms describing Parkinson-related rigidity and candidate prescriptions for the treatment of Parkinson-related rigidity in the Dongeuibogam was performed. A high-frequency medicinal herb combination group and candidates for the treatment of Parkinson-related rigidity were also selected through an analysis of medicinal herb combination frequencies. The existing literature pertaining to the potential effects of candidate herbs for Parkinson-related rigidity was reviewed.

Results and conclusions: Ten medicinal herb candidates for the treatment of Parkinson-related rigidity were selected, and their respective precedent studies were analyzed.

Keywords: Dongeuibogam (DongYiBaoGian); Parkinson's disease; rigidity; text mining.

Publication types

  • Review

MeSH terms

  • Data Mining*
  • Humans
  • Medicine, Korean Traditional*
  • Muscle Rigidity / drug therapy*
  • Parkinson Disease / drug therapy*
  • Plant Extracts / therapeutic use*

Substances

  • Plant Extracts