The Follow-Up Role of the Vestibular Evoked Myogenic Potential Test in Meniere's Disease

Acta Med Iran. 2018 Jan;56(1):43-48.

Abstract

Despite some proposed roles for the diagnostic impact of the cervical vestibular evoked myogenic potential test in the patients with Meniere's disease, the role of this test as an objective instrument in following up the patients with Meniere's disease who underwent. Intratympanic steroid injection is not cleared. In a prospective study, thirty-one adult patients with definite one-sided Meniere's disease with vertigo as main complaint refractory to medical treatments for three months, were selected. Patients underwent three times of intratympanic dexamethasone injection with one-week intervals. We performed cervical vestibular evoked myogenic potential test at first and four weeks after the last injection for all participants. We followed the patients for one year. The study results were analyzed with the chi-square test. Cervical vestibular evoked myogenic potential test could not be recorded in 26 patients (83.9%), and the test results were abnormal in the remaining 5 patients. The results were abnormal in the healthy ear of 32.3% of the patients. Despite the clinical improvement of the symptoms after intratympanic injection, the test results were not changed. Cervical vestibular evoked myogenic potential test could not be recorded in the majority of the patients with Meniere's disease; while it is usually recorded in normal ears. On the other hand, results of the cervical vestibular evoked myogenic potential test do not change during the early phase after treatment and could not be a good option for follow up and evaluating the response in this situation.

Keywords: Dexamethasone; Follow up; Intratympanic injection; Meniere’s disease; cVEMP test.

MeSH terms

  • Adult
  • Chi-Square Distribution
  • Dexamethasone / administration & dosage*
  • Female
  • Follow-Up Studies
  • Glucocorticoids / administration & dosage*
  • Humans
  • Injection, Intratympanic
  • Male
  • Meniere Disease / complications
  • Meniere Disease / drug therapy*
  • Meniere Disease / physiopathology
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome
  • Vertigo / drug therapy*
  • Vertigo / etiology
  • Vertigo / physiopathology
  • Vestibular Evoked Myogenic Potentials / drug effects*
  • Vestibular Function Tests / methods

Substances

  • Glucocorticoids
  • Dexamethasone