Concomitant diseases and their effect on disease prognosis in Meniere's disease: diabetes mellitus identified as a negative prognostic factor

Acta Otolaryngol. 2018 Jan;138(1):36-40. doi: 10.1080/00016489.2017.1373850. Epub 2017 Sep 15.

Abstract

Objective: To study comorbidities and their effect on the disease progression in Meniere's disease (MD).

Methods: Retrospective study on 350 definite MD patients diagnosed according to AAO-HNS 1995 criteria using hospital records and postal questionnaire.

Results: The prevalence of migraine, hypothyroidism, allergies, coronary heart disease and autoimmune diseases was more common in MD patients than reported in the general population of Finland. Diabetes mellitus was associated with both more severe hearing impairment (p = .033) and more frequent vertigo (p = .028) in MD patients. The number of concomitant diseases was associated with more frequent vertigo (p = .021).

Conclusions: A patient's concomitant diseases, especially diabetes, should be treated effectively because they might affect the progression of MD. Further studies on the effects of concomitant diseases on MD prognosis are needed.

Keywords: Meniere’s disease; comorbidity; diabetes mellitus; vertigo.

MeSH terms

  • Auditory Threshold
  • Comorbidity
  • Diabetes Complications / epidemiology*
  • Female
  • Finland / epidemiology
  • Humans
  • Logistic Models
  • Male
  • Meniere Disease / complications*
  • Migraine Disorders / epidemiology
  • Prevalence
  • Prognosis
  • Retrospective Studies
  • Surveys and Questionnaires
  • Vertigo