A comprehensive overview of the neuropsychiatry of Parkinson's disease: A review

Bull Menninger Clin. 2017 Winter;81(1):53-105. doi: 10.1521/bumc.2017.81.1.53.

Abstract

Parkinson's disease is a widespread neurological illness. However, its psychiatric links have also been discussed lately by many authors, which has brought more depth to the specialized field of neuropsychiatry. Neuropsychiatric complications are commonly seen in Parkinson's patients, including major depression, anxiety, psychosis and hallucination, and cognitive abnormality. Almost all of these complications have a distinct pathophysiology and treatment. In this article we review the most recent studies about the association of these symptoms with Parkinson's disease and highlight the epidemiology, diagnosis, pathophysiology, and treatment of the neuropsychiatric complications, with more emphasis on the pathophysiology of these complications.

Publication types

  • Review

MeSH terms

  • Anxiety Disorders / etiology
  • Anxiety Disorders / psychology*
  • Cognition Disorders / etiology
  • Cognition Disorders / psychology*
  • Depressive Disorder, Major / etiology
  • Depressive Disorder, Major / psychology*
  • Humans
  • Parkinson Disease / complications
  • Parkinson Disease / psychology*
  • Psychotic Disorders / etiology
  • Psychotic Disorders / psychology*