The diagnosis, clinical findings and treatment options for Parkinson's disease patients attending a tertiary referral voice clinic

J Laryngol Otol. 2017 Apr;131(4):357-362. doi: 10.1017/S0022215117000159. Epub 2017 Jan 31.

Abstract

Background: Parkinson's disease is a degenerative disorder of the central nervous system, mainly affecting motor functions including the voice. The aetiology of dysphonia changes throughout the course of disease progression.

Objectives: This study aimed to determine the laryngeal changes seen in early-, mid- and late-stage Parkinson's disease. Thirteen patients with Parkinson's disease are presented, representing the largest series of voice patients with Parkinson's disease seen in a voice clinic in the literature.

Method: Age, gender, severity of handicap caused by voice disorder and possible associated reflux symptoms were examined.

Results: Laryngeal function appeared to change gradually with progression of the disease, and may have been affected by the presence of pre-existing laryngeal pathology.

Conclusion: Laryngeal function in Parkinson's disease appears to go through a series of changes that may be helped by both therapeutic and surgical interventions. These patients should be treated within the confines of a voice clinic multidisciplinary model.

Keywords: Dysphonia; Injection; Laryngoplasty; Larynx; Medialization Laryngoplasty; Parkinson Disease.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Disease Progression*
  • Dysphonia / etiology
  • Dysphonia / physiopathology*
  • Female
  • Humans
  • Larynx / physiopathology
  • Male
  • Middle Aged
  • Parkinson Disease / complications
  • Parkinson Disease / physiopathology*
  • Referral and Consultation
  • Voice / physiology
  • Voice Disorders / etiology
  • Voice Disorders / physiopathology*