Anti-Müllerian hormone and polycystic ovary syndrome

Endokrynol Pol. 2017;68(1):74-78. doi: 10.5603/EP.a2016.0065. Epub 2016 Dec 5.

Abstract

Anti-Müllerian hormone (AMH) is a glycoprotein, a member of the transforming growth factor β family, reflecting the number of ovarian antral follicles. Polycystic ovary syndrome (PCOS) is a common endocrinopathy predisposing to infertility, and metabolic and cardiovascular complications. In our review, we discuss the role of AMH in PCOS pathophysiology and its clinical applications according to the published studies. Improvement of AMH assay validity will allow the clinical utility of this valuable biomarker to be widened. (Endokrynol Pol 2017; 68 (1): 74-78).

Keywords: AMH; PCOS; assisted reproductive technology; insulin resistance; polycystic ovarian morphology.

Publication types

  • Review

MeSH terms

  • Anti-Mullerian Hormone*
  • Female
  • Humans
  • Polycystic Ovary Syndrome / metabolism*
  • Polycystic Ovary Syndrome / physiopathology

Substances

  • Anti-Mullerian Hormone