Renal hemosiderosis and rapidly progressive glomerulonephritis associated with primary hemochromatosis

Ren Fail. 2014 Jun;36(5):814-6. doi: 10.3109/0886022X.2014.892391. Epub 2014 Mar 4.

Abstract

Hereditary hemochromatosis leads to the accumulation of iron in many organs including the liver, spleen and heart and results in injury and dysfunction of these organs. On the other hand, iron accumulation and functional impairment in kidney is extremely rare. We report a 61-year-old male patient with hereditary hemochromatosis, in whom the renal function was deteriorated rapidly. Renal biopsy revealed crescentic glomeruli and hemosiderin accumulation in tubular epithelial cells.

Keywords: Cardiac disorders; crescentic glomerulonephritis; diabetes mellitus; hereditary hemochromatosis; liver disease; skin pigmentation.

Publication types

  • Case Reports

MeSH terms

  • Fatal Outcome
  • Glomerulonephritis / etiology*
  • Hemochromatosis / complications*
  • Hemosiderosis / complications*
  • Humans
  • Male
  • Middle Aged