Chronic Obstructive Pulmonary Disease
July 2013 Issue

Each month hundreds of thousands of consumers and healthcare professionals search the National Library of Medicine's Medline database seeking the latest information on their disease/condition. Conducting a thorough and effective Medline search is both a time consuming and daunting task. At Medifocus, we have developed an effective solution to this problem: each month our staff of expert researchers searches Medline for the latest advances in research and clinical medicine for over 70 diseases / conditions. We do this with one goal in mind: to empower you to effectively take control over your health.

Here is the result of our team's work in Chronic Obstructive Pulmonary Disease this month:

1:Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial.
Authors:Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, Duerring U, Henzen C, Leibbrandt Y, Maier S, Miedinger D, Muller B, Scherr A, Schindler C, Stoeckli R, Viatte S, von Garnier C, Tamm M, Rutishauser J
Institution:Clinic of Internal Medicine, University Hospital of Basel, Switzerland.
Journal:JAMA. 2013 Jun 5;309(21):2223-31. doi: 10.1001/jama.2013.5023.

2:Effect of Jianpi therapy in treatment of chronic obstructive pulmonary disease: a systematic review.
Authors:Gao Z, Liu Y, Zhang J, Upur H
Institution:Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University & National Clinical Research Base of Traditional Chinese Medicine, Ulumuqi 830000, Xinjiang, China.
Journal:J Tradit Chin Med. 2013 Feb;33(1):1-8.

3:Ten years of tiotropium: clinical impact and patient perspectives.
Authors:Yohannes AM, Connolly MJ, Hanania NA
Institution:Manchester Metropolitan University, Department of Health Professions, UK.
Journal:Int J Chron Obstruct Pulmon Dis. 2013;8:117-25. doi: 10.2147/COPD.S28576. Epub 2013 Mar 15.

4:Combination of budesonide/formoterol more effective than fluticasone/salmeterol in preventing exacerbations in chronic obstructive pulmonary disease: the PATHOS study.
Authors:Larsson K, Janson C, Lisspers K, Jorgensen L, Stratelis G, Telg G, Stallberg B, Johansson G
Institution:Unit of Lung and Allergy Research, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Journal:J Intern Med. 2013 Jun;273(6):584-94. doi: 10.1111/joim.12067. Epub 2013 Apr 1.

5:Cardiovascular disease in COPD: mechanisms.
Authors:Maclay JD, MacNee W
Institution:Gartnavel General Hospital, Glasgow, Scotland.
Journal:Chest. 2013 Mar;143(3):798-807. doi: 10.1378/chest.12-0938.

6:Improving the quality of life in patients with chronic obstructive pulmonary disease: focus on indacaterol.
Authors:Feldman GJ
Institution:S Carolina Pharmaceutical Research, Alliance Biomedical Group International, Spartanburg, SC 29303, USA.
Journal:Int J Chron Obstruct Pulmon Dis. 2013;8:89-96. doi: 10.2147/COPD.S31209. Epub 2013 Feb 14.

7:Efficacy of pulmonary rehabilitation in patients with moderate chronic obstructive pulmonary disease: a randomized controlled trial.
Authors:Roman M, Larraz C, Gomez A, Ripoll J, Mir I, Miranda EZ, Macho A, Thomas V, Esteva M
Institution:Primary Care Majorca Department, Son Pisa Primary Health Centre, C/ Vicenc Joan Perello Ribes, 65, Palma de Mallorca, Baleares, Spain.
Journal:BMC Fam Pract. 2013 Feb 11;14:21. doi: 10.1186/1471-2296-14-21.

8:Inhaled corticosteroids in lung diseases.
Authors:Raissy HH, Kelly HW, Harkins M, Szefler SJ
Institution:Department of Pediatrics, School of Medicine, University of New Mexico, Albuquerque, NM, USA.
Journal:Am J Respir Crit Care Med. 2013 Apr 15;187(8):798-803. doi: 10.1164/rccm.201210-1853PP.

9:Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease.
Authors:Barnes PJ
Institution:National Heart and Lung Institute, Imperial College, London, United Kingdom.
Journal:J Allergy Clin Immunol. 2013 Mar;131(3):636-45. doi: 10.1016/j.jaci.2012.12.1564. Epub 2013 Jan 26.

10:Clinical characteristics, response to exercise training, and outcomes in patients with heart failure and chronic obstructive pulmonary disease: findings from Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION).
Authors:Mentz RJ, Schulte PJ, Fleg JL, Fiuzat M, Kraus WE, Pina IL, Keteyian SJ, Kitzman DW, Whellan DJ, Ellis SJ, O'Connor CM
Institution:Duke University Medical Center, Durham, NC, USA.
Journal:Am Heart J. 2013 Feb;165(2):193-9. doi: 10.1016/j.ahj.2012.10.029. Epub 2012 Nov 28.

11:beta2-agonist therapy in lung disease.
Authors:Cazzola M, Page CP, Rogliani P, Matera MG
Institution:Department of System Medicine, University of Rome Tor Vergata, Via Montpellier 1, Rome, Italy.
Journal:Am J Respir Crit Care Med. 2013 Apr 1;187(7):690-6. doi: 10.1164/rccm.201209-1739PP.

12:COPD exacerbations: causes, prevention, and treatment.
Authors:Mackay AJ, Hurst JR
Institution:Academic Unit of Respiratory Medicine, Royal Free Campus, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK.
Journal:Immunol Allergy Clin North Am. 2013 Feb;33(1):95-115. doi: 10.1016/j.iac.2012.10.006. Epub 2012 Dec 21.

13:COPD exacerbations.
Authors:Burt L, Corbridge S
Institution:Department of Biobehavioral Health Science, University of Illinois at Chicago, College of Nursing, USA.
Journal:Am J Nurs. 2013 Feb;113(2):34-43; quiz 44. doi: 10.1097/01.NAJ.0000426688.96330.60.

14:Systematic review and meta-analysis of prophylactic antibiotics in COPD and/or chronic bronchitis.
Authors:Lee JS, Park DA, Hong Y, Jo KW, Lee SW, Huh JW, Oh YM, Lee SD
Institution:Department of Pulmonary and Critical Care Medicine, and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Journal:Int J Tuberc Lung Dis. 2013 Feb;17(2):153-62. doi: 10.5588/ijtld.12.0401.

15:Use of nebulised magnesium sulphate as an adjuvant in the treatment of acute exacerbations of COPD in adults: a randomised double-blind placebo-controlled trial.
Authors:Edwards L, Shirtcliffe P, Wadsworth K, Healy B, Jefferies S, Weatherall M, Beasley R
Institution:Medical Research Institute of New Zealand, Wellington, New Zealand.
Journal:Thorax. 2013 Apr;68(4):338-43. doi: 10.1136/thoraxjnl-2012-202225. Epub 2013 Jan 7.

16:Monoclonal antibodies for asthma and chronic obstructive pulmonary disease.
Authors:Antoniu SA
Institution:University of Medicine and Pharmacy, Pulmonary Disease University Hospital, Division of Pulmonary Disease, Iasi 700115, Romania.
Journal:Expert Opin Biol Ther. 2013 Feb;13(2):257-68. doi: 10.1517/14712598.2012.758247. Epub 2013 Jan 3.

17:Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization.
Authors:Polkey MI, Spruit MA, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agusti A, Bakke PS, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, Miller BE, Crim C, Yates J, Wouters EF, Celli B
Institution:NIHR Respiratory Biomedical Research Unit at the Royal Brompton Hospital and Imperial College London, London, United Kingdom.
Journal:Am J Respir Crit Care Med. 2013 Feb 15;187(4):382-6. doi: 10.1164/rccm.201209-1596OC. Epub 2012 Dec 21.

18:Effects of long-acting bronchodilators in COPD patients according to COPD severity and ICS use.
Authors:Decramer M, Dahl R, Kornmann O, Korn S, Lawrence D, McBryan D
Institution:Respiratory Division, University Hospitals, Herestraat 49, B-3000 Leuven, Belgium.
Journal:Respir Med. 2013 Feb;107(2):223-32. doi: 10.1016/j.rmed.2012.10.022. Epub 2012 Dec 6.

19:Chronic bronchitis and chronic obstructive pulmonary disease.
Authors:Kim V, Criner GJ
Institution:Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Journal:Am J Respir Crit Care Med. 2013 Feb 1;187(3):228-37. doi: 10.1164/rccm.201210-1843CI. Epub 2012 Nov 29.

20:TNFalpha antagonists for acute exacerbations of COPD: a randomised double-blind controlled trial.
Authors:Aaron SD, Vandemheen KL, Maltais F, Field SK, Sin DD, Bourbeau J, Marciniuk DD, FitzGerald JM, Nair P, Mallick R
Institution:Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
Journal:Thorax. 2013 Feb;68(2):142-8. doi: 10.1136/thoraxjnl-2012-202432. Epub 2012 Nov 17.

21:Relationship between daily physical activity and exercise capacity in patients with COPD.
Authors:Zwerink M, van der Palen J, van der Valk P, Brusse-Keizer M, Effing T
Institution:Medisch Spectrum Twente, Department of Pulmonary Medicine, The Netherlands.
Journal:Respir Med. 2013 Feb;107(2):242-8. doi: 10.1016/j.rmed.2012.09.018. Epub 2012 Oct 22.

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